Drug Discovery and Development: Technology in Transition

ISBN-13: 9780702078040 / Angielski / Miękka / 2021

Raymond G. Hill; Duncan Richards

Spis treści

Section 1 Introduction and Background

1. Development of the pharmaceutical industry

2. Nature of disease and purpose of therapy

3. Therapeutic modalities

Section 2 Drug Discovery

4. Drug target identification

5. Selecting the modality and planning the project

6. High throughput screening

7. Medicinal Chemistry

8. Biopharmaceuticals and related molecules

9. Emerging modalities: nucleotide based therapy, cell based therapy, gene therapy / Novel and Advanced Process

10. Metabolism and Pharmacokinetical strategies.

11. Role of pharmacology to include pharmacology of newer modalities

12. In vitro in vivo translation

13. Vaccines

Section 3 Drug Development

14. Drug development introduction

15. Drug safety

16. Pharmaceutical development

17. Clinical development

18. Clinical imaging

19. Intellectual property

20. Regulatory affairs

21. Marketing and Patient access to medicines

Section 4 Facts and Figures

22. Facts and Figures; and the Future