Drug Delivery System

ISBN-13: 9781493954643 / Angielski / Miękka / 2016 / 280 str.

Kewal K. Jain

Opis

Drug Delivery Systems, Second Edition expands upon the previous edition with current, detailed methods and technologies to further study drug delivery. With new chapters on nanobiotechnology techniques, experimental methods and the clinical use for the intrathecal delivery of analgesics. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls.Authoritative and practical, Drug Delivery Systems, Second Edition will be useful for pharmaceutical scientists as well as well as physicians both in the academic institutions and in the industry.

Spis treści

1. Current Status and Future Prospects of Drug Delivery Systems

K. K. Jain

 2. A Method for Screening Mitochondrial Fusogenic Envelopes for use in Mitochondrial Drug Delivery

Yuma Yamada and Hideyoshi Harashima

 3. Ultrasound-directed, Site-specific Gene Delivery

Jason Castle    and   Steven B. Feinstein

 4. Synthesis of Thermoresponsive Polymers for Drug DeliverySushil Mishra, Arnab De, and Subho Mozumdar

 5. Recombinant Stem Cells as Carriers for Cancer Gene Therapy

Yu-Lan Hu and  Jian-Qing Gao

 6. Microfluidic-based Manufacture of siRNA-lipid Nanoparticles for Therapeutic Applications

Colin Walsh, Kevin Ou, Nathan M. Belliveau, Tim J. Leaver, Andre W. Wild, Jens Huft, Paulo J. Lin, Sam Chen, Alex K. Leung, Justin B. Lee, Carl L. Hansen, Robert J. Taylor, Euan C. Ramsay, Pieter R. Cullis

 7. Microneedle-iontophoresis Combinations for Enhanced Transdermal Drug Delivery

Ryan F. Donnelly, Martin J. Garland, and Ahlam Zaid Alkilani

 8. Polymer Nanoparticle-based Controlled Pulmonary Drug Delivery

Moritz Beck-Broichsitter, Alexandra C. Dalla-Bona, Thomas Kissel, Werner Seeger, and Thomas Schmehl

 9. Antibody Labeling with Radioiodine and Radiometals

Suprit Gupta, Surinder Batra, and Maneesh Jain

 10. Self Assembling Peptide -based Delivery of Therapeutics for Myocardial Infarction

Archana V. Boopathy and Michael E. Davis

 11. Applications of Chitosan Nanoparticles in Drug Delivery

H. A. Tajmir-Riahi, Sh. Nafisi,  S. Sanyakamdhorn , D. Agudelo and P. Chanphai

 12. A Method for Evaluating Nanoparticle Transport through the Blood Brain Barrier in vitro

Daniela Guarnieri, Ornella Muscetti and Paolo A. Netti

 13. Bacterial Systems for Gene Delivery to Systemic Tumours

Joanne Cummins, Michelle Cronin, Jan Peter van Pijkeren, Cormac G.M. Gahan and Mark Tangney

 14. Synthesis of a Smart Nanovehicle for Targeting Liver

Arnab De, Sushil Mishra, Seema Garg, and Subho Mozumdar

15. Intranasal Delivery of Chitosan-siRNA Nanoparticle Formulation to the Brain

Meenakshi Malhotra, Catherine Tomaro-Duchesneau, Shyamali Saha, and Satya Prakash

 16. Intrathecal Delivery of Analgesics

Jose De Andres, Juan Marcos Asensio-Samper, and  Gustavo Fabregat-Cid