Diffusion Tensor Imaging and Fractional Anisotropy: Imaging Biomarkers in Early Parkinson’s Disease

ISBN-13: 9789811950001 / Angielski / Twarda / 2022 / 157 str.

Rahul P. Kotian; Prakashini Koteshwar

Opis

The book covers all aspects of one of the most advanced magnetic resonance imaging techniques, namely Diffusion Tensor Imaging (DTI) and Fractional Anisotropy (FA) values in early Parkinson’s disease (PD) patients. It provides step-by-step descriptions of DTI and its use in the early diagnosis of Parkinson’s disease by using FA values at several grey and white matter regions of the brain with helpful MRI DTI images. It includes clear flow charts with MRI DTI imaging protocol for Parkinson’s disease to aid in early diagnosis and treatment. The book covers essential information on anatomy and pathology in Parkinson’s disease and includes dedicated chapters on diffusion tensor imaging and FA in Parkinson’s disease. Additionally, it covers the role of magnetic resonance imaging in Parkinson’s disease with routine findings for Parkinson’s disease in MRI, followed by advanced imaging biomarkers and predictors in Parkinson’s disease.

 

The book will assist the practitioners in the early detection of Parkinson’s disease using specific imaging biomarkers with the help of FA values, which will help in the early treatment of PD patients and thus extend and improve their quality of life. It will also be relevant for MD radiology, M.Sc. medical imaging technology students/trainees and Ph.D. medical imaging graduates as well as B.Sc MIT students.

Spis treści

1              History & Basic Principles of Magnetic Resonance Imaging

2              Image contrast mechanisms in Diffusion Weighted and Diffusion Tensor Imaging

3              Diffusion weighted imaging physics and techniques

4              Advanced MRI Neuro imaging technique – Diffusion Tensor Imaging

5              Fractional anisotropy: Scalar derivative of Diffusion Tensor Imaging

6              Diffusion Tensor Imaging Instrumentation

7              Diffusion tensor imaging and fractional anisotropy protocol at 1.5 Tesla MRI for Early Parkinson’s disease

8              DTI and FA: Introduction to Parkinson’s disease

9              Evidence of fractional anisotropy in Parkinson’s disease

10           FA characteristics as imaging biomarkers among Indian population in early Parkinson’s disease

O autorze

Dr Rahul P Kotian is currently working as an Assistant Professor in the medical imaging sciences program of College of Health Sciences, Gulf Medical University, Ajman, the United Arab Emirates from September 2021 and has a teaching and research experience of 13 years in the field of medical imaging. Dr Rahul served at Manipal College of Health Professions, Manipal Academy of Higher Education,Manipal, Karnataka, India for over a decade in different capacities from 2009 to 2019. He was the former Dean and Professor at the College of Allied Health Sciences, NIMS University, Jaipur, Rajasthan.Dr Rahul was also the Associate Dean at the College of Allied Health Sciences, Srinivas University, Mukka, Mangalore, Karnataka, India.He was also the Radiation Safety Officer Level I at Kasturba Medical College and Hospital, Manipal Academy of Higher Education(2011-2014, 2014-2017 and 2017-2019). 

Dr Rahul is a doctorate in magnetic resonance imaging and received his PhD from Manipal College of Health Professions, Manipal Academy of Higher Education, Manipal, Karnataka, India.He was the first clinical PhD in magnetic resonance imaging and Parkinson’s disease in medical imaging in India.Dr Rahul was recognized with honorary doctorate for his excellence in the field of medical imaging technologyin 2021 from Bharat Virtual University for Peace and Education (Unit of United Nations Organization, Geneva). 

Dr Rahul has published several scientific research papers in the field of radiology and magnetic resonance imaging (MRI), diffusion tensor imaging(DTI), fractional anisotropy(FA), Parkinson’s disease (PD), computed tomography(CT) and radiation protection. He is a reviewer for many Scopus indexed peer-reviewed journals.He is recognized internationally and nationally as a leader in the field of medical imaging in DTI and FA imaging and has presented several research papers. He is also one of the keynote and guest speakers at various international and national conferences.

Dr Prakashini Koteshwar is a Professor and Head of the department of radiology, Kasturba Medical College (KMC), Manipal Academy of Higher Education, Manipal, Karnataka, India and serving at KMC since 2006. She perused her MD degree in radiodiagnosis and imaging from KMC, Manipal Academy of Higher Education.During her tenure, she initiated different academic programmes and recently commenced the ‘interventional division’ which is going to provide all high-endsemi-invasive non-surgical options of treatment, for various emergency and non-emergency conditions. 

Dr Koteshwar’s area of interest is neuroimaging, cardiovascular imaging and interventional radiology. She has completed Level I accreditation in CT and MRI reporting of cardiac imaging. She has been working with AI-based algorithm applications in brain tumours and computational flow dynamics in carotid, and renal arteries and presently on ‘the effect of peristalsis on ureteric flow’.She has several publications to her credit both in national and international reputed journals on clinical, radiological and AI aspects. She has been guiding several research and PhD projects for MD radiology, MSc medical imaging students and also engineering graduates. 

Dr Koteshwar is an auditor of NABH, ISO accreditation and is in charge of the documents related to MCI recognition for MBBS and MD radiology. She is also currently working with grant projects of DST/SERB and industry collaborations too.