Developmental Genomics of Ascidians

ISBN-13: 9781118656181 / Angielski / Twarda / 2014 / 216 str.

Noriyuki Satoh

Opis

The simplicity and lack of redundancy in their regulatory genes have made ascidians one of the most useful species in studying developmental genomics. In Developmental Genomics of Ascidians, Dr. Noriyuki Satoh explains the developmental genomics of ascidians, stresses the simplicity of Ciona developmental system, and emphasizes single-cell level analyses. This book actively accentuates the advantages of using ascidians as model organisms in an up-and-coming field of developmental genomics.

Recenzje

"In his preface, the author describes Developmental Genomics of Ascidians as his last and largest contribution to ascidian developmental biology (p. xi). This book is indeed a major accomplishment and a great resource for the community" (The Quarterly Review of Biology 2016)

Spis treści

PREFACE ix

CHAPTER 1 A BRIEF INTRODUCTION TO ASCIDIANS 1

CHAPTER 2 THE DEVELOPMENT OF TADPOLE LARVAE AND SESSILE JUVENILES 9

CHAPTER 3 GENOMICS, TRANSCRIPTOMICS, AND PROTEOMICS 19

CHAPTER 4 RESEARCH TOOLS 31

CHAPTER 5 THE FUNCTION AND REGULATION OF MATERNAL TRANSCRIPTS 41

CHAPTER 6 LARVAL TAIL MUSCLE 53

CHAPTER 7 ENDODERM 63

CHAPTER 8 EPIDERMIS 69

CHAPTER 9 NOTOCHORD 77

CHAPTER 10 THE LARVAL AND ADULT NERVOUS SYSTEMS 89

CHAPTER 11 MESENCHYME 107

CHAPTER 12 MAKING BLUEPRINT OF CHORDATE BODY: DYNAMIC ACTIVITIES OF REGULATORY GENES 113

CHAPTER 13 DEVELOPMENT OF THE JUVENILE HEART 137

CHAPTER 14 GERM–CELL LINE, GAMETES, FERTILIZATION, AND METAMORPHOSIS 145

CHAPTER 15 INNATE IMMUNE SYSTEM AND BLOOD CELLS 159

CHAPTER 16 COLONIAL ASCIDIANS: ASEXUAL REPRODUCTION AND COLONY SPECIFICITY 167

CHAPTER 17 EVOLUTIONARY DEVELOPMENTAL GENOMICS 175

INDEX 193

Blurb

A comprehensive discussion of the developmental genomics of the model organism, ascidians

Ascidians are quickly becoming one of the most suitable experimental systems in which to explore the cellular and molecular mechanisms of embryonic cell specification and differentiation. The simplicity and lack of redundancy in their regulatory genes have made ascidians one of the most useful species in studying developmental genomics.

In Developmental Genomics of Ascidians, Dr. Noriyuki Satoh explains the developmental genomics of ascidians and the advantages of using them as model organisms; stresses the simplicity of the Ciona developmental system; and emphasizes single–cell level analyses.

Following a brief introduction to ascidians, the book provides in–depth chapter coverage of:

• The development of tadpole larvae and sessile juveniles
• Genomics, transcriptomics, and proteomics
• Research tools
• The function and regulation of maternal transcripts
• Larval tail muscle
• Endoderm
• Epidermis
• Notochord
• The nervous system
• Mesenchyme
• Making a blueprint of the chordate body: dynamic activities of regulatory genes
• Development of the juvenile heart
• Germ cell lines and stem cells
• Self/non–self recognition systems and the ascidian innate immunity system
• Evolutionary embryology of ascidians

Developmental Genomics of Ascidians is an ideal book for researchers and students in developmental biology, cell biology, molecular biology, genome sciences, and more.