Dendritic Spines

ISBN-13: 9783031361586 / Angielski / Twarda / 2023

Opis

This reference provides detailed coverage of dendritic spines, the fascinating neuronal components that modulate synaptic transmission, development, strength, and plasticity and are involved in the function of multiple areas of the nervous system. The density, shape, and function of spines may indicate the cellular connectivity and synaptic plasticity in normal and pathological conditions. This field has undergone dramatic advances in terms of techniques and experimental findings from in vitro to in vivo data, from animal models to human neurons, and computational models using artificial intelligence. To address these cutting-edge findings, the book provides state-of-the-art, comprehensive coverage with chapters written by the leading international researchers in the field. The authors consider the multiple implications for the study of dendritic spines with broad implications in the neurosciences and related areas.  

Spis treści

Contents

List of Chapters and authors

Chapter 1 -  Introduction

What are dendritic spines?

Alberto A. Rasia-Filho, Maria Elisa Calcagnotto and Oliver von Bohlen und Halbach

Chapter 2 - Techniques to render dendritic spines visible in the microscope

Floris G. Wouterlood

Chapter 3 -  Electrophysiology of dendritic spines: information processing, dynamic compartmentalization and synaptic plasticity

Joseane R. Marafiga and Maria Elisa Calcagnotto

Chapter 4 -  Dendritic spines, synaptogenesis and synaptic pruning for the developmental organization of brain circuits

Zdravko Petanjek, Ivan Banovac, Dora Sedmak, and Ana Hladnik

Chapter 5 -  Neurotrophic factors and dendritic spines

Oliver von Bohlen und Halbach

Chapter 6 -  Glial cell modulation of dendritic spine structure and synaptic function

Alberto A. Rasia-Filho, Maria Elisa Calcagnotto and Oliver von Bohlen und Halbach

Chapter 7 - Dendritic spines in learning and memory: from first discoveries to current insights

Nicolas Heck and Marc Dos Santos

Chapter 8 - Steroid hormone interaction with dendritic spines: implications for neuropsychiatric disease

Maya Frankfurt, Zeinab Nassrallah and Victoria Luine 

Chapter 9 - Morphological features of human dendritic spines

Josué Renner and Alberto A. Rasia-Filho

O autorze

Alberto A. Rasia-Filho, MD, PhD, is Professor, ​ Department of Basic Sciences/Physiology and Graduate Program in Biosciences, Federal University of Health Sciences of Porto Alegre, and Graduate Program in Neuroscience, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil

Maria Elisa Calcagnotto, MD, PhD, is Professor, Department of Biochemistry, Graduate Program in Biochemistry, Graduate Program in Neuroscience, and Graduate Program in Psychiatry and Behavioral Science, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil 

Oliver von Bohlen und Halbach, PhD, is Professor, Institut für Anatomie und Zellbiologie,  Universitätsmedizin Greifswald, Greifswald, Germany