1. Introduction to Data Science 2. Toolboxes for Data Scientists 3. Machine Learning and Deep Learning: A Concise Overview 4. Artificial Intelligence 5. Data Privacy and Data Trust 6. Visual Data Analysis and Complex Data Analysis 7. Big Data programming with Apache Spark and Hadoop 8. Information Retrieval and Recommender Systems 9. Statistical Natural Language Processing for Sentiment Analysis 10. Parallel Computing and High-Performance Computing 11. Data Science, Genomics, Genomes, and Genetics 12. Blockchain Technology for securing Genomic data 13. Cloud, edge, fog, etc., for communicating and storing data for Genome 14. Open Issues, Challenges and Future Research Directions towards Data science and Genomics 15. Privacy Laws 16. Ethical Concerns 17. Self-study questions 18. Problem-based learning 19. Key Terms/ Glossary 20. Appendix - Keeping up to Date 21. Bibliography