Cytotoxic giant-cell induction & phytoconstituents of Yellow Oleander

ISBN-13: 9786202516785 / Angielski / Miękka / 2020 / 72 str.

Navya Siby; Shija Jacob; John E. Thoppil

Opis

This book entitled "Cytotoxic giant-cell induction & phytoconstituents of Yellow Oleander, Cascabela thevetia (L.) Lippold [Apocynaceae] " reveals the cytotoxicity of C. thevetia, its phytochemical analysis and in situ visualisation of cell death using Evans blue assay. Yellow oleander, a tropical evergreen shrub is a native of West Indies, Southern Mexico and America. The plant possesses phytoconstituents like alkaloids, flavonoids, phenols, terpenoids, saponins, phlobatannins, steroids, tannins, coumarins, proteins and amino acids. A wide spectrum of clastogenic abnormalities like the giant cells, the strap cells, nuclear budding & lesions, cytoplasmic shrinkage & vacuolation, nuclear & chromosome erosion, apoptotic bodies, nuclear disintegration & extrusion, nuclear diminution, & fragmentation, apoptotic fragmentation of chromatin, nuclear peak formation, pulverization, multiple chromosome bridges, etc. were observed. The non-clastogenic abnormalities scored include micronucleus, bi- & tri-nucleate cells, triple micronuclei, the diagonal arrangement of chromosomes, tripolar anaphase, etc. The study unveils the potential cytotoxic and phytochemical constituents of C. thevetia.

O autorze

Siby, Navya
The first author Navya Siby is a student and the second author Shija Jacob is a faculty of the Department of Biotechnology & Botany, St.Berchmans College, Changanassery, Kottayam, Kerala, India. The third author Prof. John E. Thoppil is a faculty of the Department of Botany, University of Calicut, Kerala, India.