Cytotoxic Effect of Doxorubicin and Autophagy Modulation on TNBC

ISBN-13: 9786139444953 / Angielski / Miękka / 2019 / 124 str.

Eman Salah El-Shafey

Opis

Doxorubicin is regarded as the most therapeutic active agent available for triple-negative breast cancer (TNBC) treatment. However, the development of drug resistance and toxicity limits its effectiveness. Thus, developing novel strategies for TNBC treatment remains a significant challenge and doxorubicin-based combinations either by metal complexes (Copper I nicotinate complex) or with autophagy modulators could provide novel strategies and alternative strategies contributed to cancer cell death pathways, autophagy and apoptosis.

O autorze

El-Shafey, Eman Salah
Eman Salah El-Shafey is PhD post research fellow,Department of chemistry, Biochemistry specialization facultyof science Damietta; Egypt. She received BSc(chemistry/biochemistry) from Mansoura University,MSc in biochemistry and PhD in biochemistry fromDamietta University. She is interested in studying ofBiochemistry and Cell Biology.