Cytokines in the Genesis and Treatment of Cancer

ISBN-13: 9781617372032 / Angielski / Miękka / 2010 / 482 str.

Michael A. Caligiuri; Michael T. Lotze

Opis

Cytokines in the Genesis and Treatment of Cancer provides a comprehensive picture of the dual role of host responses in promoting and inhibiting tumor progression. This volume represents an important investigation into the emerging intersection of cancer biology and cancer immunology. Divided into four sections, the volume s first three parts focus on cytokines in the genesis of cancer. The final section describes the notable progress both in animal models and humans in demonstrating the use of cytokine or anticytokine therapies for the prevention and treatment of cancer. Cytokines in the Genesis and Treatment of Cancer brings together an impressive array of internationally distinguished investigators who are devoted to the study of cytokines and cancer. Together, they produce an insightful, comprehensive discussion of cytokines and cancer that will serve as the perfect reference for all those working in the field."

Recenzje

From the reviews:

"...brings together an impressive array of internationally distinguished investigators who are devoted to the study of cytokines and cancer. Together,, they produce an insightful, comprehensive discussion of cytokines and cancer that will serve as the perfect reference for all those working in the field." -Anticancer Research

"This is a collection of papers from a large number of authors on the role of cytokines in the genesis of neoplastic diseases including metastatic spreads and the potential role in therapy. ... Chronic cytokine production can contribute to the generation and progression of cancer. Mechanisms involved in this process are described in the many chapters of this volume. The book is highly recommended to all of those involved in the study of neoplastic diseases." (Julian L. Ambrus, The Journal of Medicine, March, 2008)

"This new volume in Humana's series will be necessary reading for researchers, oncologists, pharmacologists, radiotherapists." (Tumori, Vol. 93, 2007)

Spis treści

Cytokines in the Genesis and Treatment of Cancer Co-Editors: Michael A. Caligiuri and Michael T. Lotze Introduction 1. Overview and Introduction to Cancer and Inflammation Michael A. Caligiuri and Michael T. Lotze Part I. Cytokines in the Genesis of Cancer Infectious Agents, Cytokines and Cancer 2. Helicobacter Pylori Richard M. Peek, Jr. 3. HTLV-1 Michael Lairmore and Lee Ratner 4. Herpes Viruses Frank J. Jenkins and Heather R. Hensler Cytokines and Carcinogenesis 5. TNF Mark DeWitte, David J. Shealy, Marian Nakada, and G. Mark Anderson 6. TGF-Š Alyssa R. Bonine, Brian K. Law and Harold L. Moses 7. Interleukin 1 (IL-1) Family of Cytokines Michael T. Lotze 8. IL-4/13 Koji Kawakami and Raj Puri 9. IL-6 and Castleman's disease Norihiro Nishimoto 10. Interleukin 10 (IL-10) Family of Cytokines Shin-ichiro Fujii and Michael Lotze 11. Cytokines in Multiple Myeloma: Therapeutic Implications Dharminder Chauhan, Teru Hideshima and Kenneth Anderson 12. Murine Cytokine Models and the Genesis of Cancer Todd A. Fehniger, Megan A. Cooper, Michael A. Caligiuri 13. Experimental Models of Cytokines and Cancer Prevention Mark J. Smyth, Erika Cretney, Shayna E.A. Street and Yoshihiro Hayakawa Cytokines and Tumor Stroma/Metastasis 14. Cytokines in the Tumor Stroma Michael C. Ostrowski 15. Cytokines and Angiogenesis in Tumors Sharmila Roy-Chowdhury and Charles K. Brown 16. Chemokines and Receptor Expression in Tumor Progression Paola Allavena, Federica Marchesi and Alberto Mantovani 17. The Biology of Cancer Cachexia: Role of TNF± Denis Guttridge Part II: Cytokines in The Treatment Of Cancer 18. IL-2 Kim Margolin and JoeClark 19. IL-12 Timothy E. Bael and Jared Gollob 20. The Type I Interferon Family Stergios J. Moschos, Gregory B. Lesinski, William E. Carson, III, and John M. Kirkwood 21. Combination Cytokine Therapy Seth Cohen and Howard Kaufman 22. Novel Strategies for Targeting Cytokine Administration Paul M. Sondel, Jackie Hank, Mark Albertini and Stephen D. Gilles 23. Cytokines and Cancer Vaccines Hideho Okada and Michael T. Lotze 24. Anti-cytokine Therapy Miguel A. Villalona-Calero 25. Cytokines in the Supportive Care of Cancer John A. Glaspy