Cytokines and the CNS

ISBN-13: 9780367391935 / Angielski / Miękka / 2019 / 384 str.

Richard M. Ransohoff; Etty N. Benveniste

Opis

The similarity between factors involved in inflammation or immunity and those implicated in neural development, physiology, and repair has become so apparent that familiarity with cytokines must now be considered an essential element in both the immunobiologist’s and neurobiologist’s cognitive tool-kit. Designed for both clinicians and researchers in neurobiology and immunology, this work features the most innovative researchers in the field. They offer deepened insight into how cytokine action impacts the physiology and pathology of the CNS. Taking a systems approach, they look at immunity, inflammation, and development processes, rather than individual cell types; and discusses specific applications of cytokine biology to the treatment of disease

Spis treści

The CNS: Cells, Tissues and Reactions to Insult. Cytokines – Wherefrom and Whereto. Cytokine Receptors. Cytokines and Signaling. Inflammatory Complexities in the CNS: New Insights into the Effects of Intracellular Redox State and Viral Infection in Modulating the Biology of Oligodendrocytes and Their Precursor Cells. Cytokines and Development of the Nervous System. Cytokines and CNS Inflammation. Cytokines and Immune Regulation in the Nervous System. Cytokines and Neurodegeneration. Cytokine Expression and Signaling in Brain Tumors. Cytokines and Defense Pathology of the CNS. Cytokines and Multiple Sclerosis. Cytokines in Brain Trauma and Spinal Cord Injury. Cytokine-Based Therapeutics for Intrinsic CNS Disease Processes.

O autorze

Richard M. Ransohoff, Etty N. Benveniste