Part 1: Regional Innovation Systems 1. The Regionalization of Knowledge: The Territorial Basis of Development 2. Creative Regions and Globalising Social Capital – Connecting Foreign ICT Experts to Finnish Innovation Environments 3. Connectivity and Co-Location in Innovation Processes of Dutch Firms 4. On Strengthening the Knowledge Base of Knowledge-Intensive SMEs in Less-Favoured Regions in Finland Part 2: Cluster Evolution, Variety and Policy 5. Regional Innovation Clusters: Evaluation of the South East Brabant Cluster Scheme 6. Cluster Emergence: A Comparative Study of Two Cases in North Jutland, Denmark 7. The Knowledge-Space Dynamic in the British Biotechnology Industry: Function, Relation, and Association 8. Cultural and Creative Industries in Places of 'High Culture' – The Case of the Art City of Florence 9. Reflections on Innovative Alliances Involving Technological Science and the Creative Industry – A Case Study Involving the Roskilde Region and Musicon Valley Part 3: Knowledge Transfer, R&D Outsourcing, Open Innovation 10. Research, Knowledge and Open Innovation: Spatial Impacts upon Organization of Knowledge-Intensive Industry Clusters 11. The Outsourcing of Knowledge Production and its Implications for Regional Path Dependence 12. Creativity and Openness: Outsourcing of Knowledge Intensive Services as a Challenge for Innovation Systems in a Metropolitan Region 13. Boundary Spanning and the ‘Knowledge Community’