Coronavirus Therapeutics – Volume I: Basic Science and Therapy Development

ISBN-13: 9783030851118 / Angielski / Miękka / 2023 / 222 str.

Alexzander A. a. Asea; Punit Kaur

Opis

The book Coronavirus Therapeutics Volume I provides the most comprehensive review on contemporary knowledge on the origin and structural biology and molecular aspects of Coronaviruses. This also describes the etiology and pathogeny and therapeutic targets including vaccine drug candidates against Coronaviruses in the light of current scientific knowledge. Using an integrative approach to the understanding of Coronaviruses structure, function and immunobiology, the contributors provide a synopsis of novel mechanisms by which Coronaviruses can be treated.Key basic and clinical research laboratories from major universities, academic medical hospitals, biotechnology and pharmaceutical laboratories around the world have contributed articles that review present research activity on the role of heat shock proteins in human diseases and importantly project the field into the future. The book is a must read for graduate students. medical students, basic science researchers and postdoctoral scholars in the fields of Cancer Biology, Oncology, Cardiovascular Diseases, Microbiology, Inflammation, Translational Medicine, Clinical Research, Biotechnology, Cell & Molecular Medicine, Pharmaceutical Scientists and Researchers involved in Drug Discovery.

Spis treści

1. Origin and structural biology of Novel Coronavirus (SARS-CoV-2). Rahul Mallick, University of Eastern Finland and Asim K. Duttaroy, University of Oslo. 

2. The Molecular Virology of Coronaviruses with Special Reference to SARS-CoV-2. Muhammad Munir, Lancaster University, UK. (CTP)

3. Epidemiology, transmission and molecular immunopathology of SARS-CoV-2. Rahul Mallick, University of Eastern Finland and Asim K. Duttaroy, University of Oslo.

4. Epidemiology and Etiopathogeny of Covid-19.  Modesto Leite Rolim Neto, School of Medicine, Universidade Federal do Cariri, Brasil.

5. Immunological and Hematological Response in COVID-19. Mariusz Kowalewski. Central Clinical Hospital of the Ministry of Interior and Administration. Warsaw, Poland.

6. Toll-like receptors (TLRs) as Therapeutic Targets for Treating SARS-CoV-2: An Immunobiological Perspective. Suprabhat Mukherjee. Kazi Nazrul University, India.

7. Potential drug strategies to target Coronaviruses. Kasturi Sarkar and Parames C. Sil1. Division of Molecular Medicine. Bose Institute. India. 

8. Possible therapeutic intervention strategies for COVID-19 by manipulating the cellular proteostasis network. Koyeli Mapa. Department of Life Sciences, Shiv Nadar University, India. 

9. The potential impact of statins in the treatment of patients with COVID-19 infection. Amir Avan. Mashhad University of Medical Sciences, Mashhad, Iran. 

10. Anticoronavirus activity of water-soluble pristine C60 fullerenes: in vitro and in silico screening. Uwe Ritter. National University of Kyiv, Kyiv, Ukraine. 

11. Application of Nanoscale materials and nanotechnology against viral infection: A special focus on Coronaviruses. Subhankar Paul. Institute of Technology Rourkela, Orissa, India. 

12. Obesity: A Risk Factor for Covid-19 – Geetha Suryakumar, Defence Institute of Physiology and Allied Sciences, India.

13. Cytokine Storm and Failed Resolution in COVID-19: Taking Cue from Multiple Sclerosis. Shailendra Giri. Henry Ford Hospital, USA.

O autorze

Prof. Dr. Alexzander A. A. Asea is a highly innovative and accomplished world renowned clinical and basic research scientist and visionary executive leader who has exceptional experience spearheading clinical and basic science research, training, education, and commercialization initiatives within top ranked academic biomedical institutes. Prof. Dr. Asea’s initial findings studying the effects of Hsp72 on human monocytes lead to the proposal of a novel paradigm that Hsp72, previously known to be an intracellular molecular chaperones, can be found in the extracellular milieu where it has regulatory effects on immuno-competent cells - a term now called chaperokine. Prof. Dr. Alexzander Asea is also President & CEO of NampEVA BioTherapeutics, a company dedicated to providing affordable medicines to patients in emerging nations. Prof. Dr. Asea has authored over 320 scientific publications including peer-reviewed articles, reviews, books, book chapters, editorials, and news headliners in a wide range of biomedical-related disciplines. Prof. Dr. Asea is the Editor-in-Chief of the widely successful book series Heat Shock Proteins (Springer Nature Publishing) and is an editorial board member of numerous scientific peer-reviewed journals. Prof. Dr. Asea is at the University of Toledo College of Medicine and Life Sciences in Toledo, USA.

Dr. Punit Kaur is an expert in onco-proteogenomics, with extensive training and experience in quantitative mass spectrometry imaging, protein chemistry and biomarker discovery. Dr. Kaur’s main research focus is on the use of heat-induced nanotechnology in combination with radiotherapy and chemotherapy in the cancer stem cell therapy. Dr. Kaur has published more than 80 scientific articles, book chapters, and reviews, and currently serves as editorial board member for the European Journal of Cancer Prevention and the Journal of Proteomics and Bioinformatics. Dr. Kaur is the Associate Editor of the highly successful Heat Shock Proteins book series by Springer Nature Publishers. Currently, Dr. Kaur is at the University of Toledo College of Medicine and Life Sciences in Toledo, USA.

Blurb

The book Coronavirus Therapeutics Volume I provides the most comprehensive review on contemporary knowledge on the origin, structural biology and molecular aspects of Coronaviruses. It also describes the etiology and pathogeny and therapeutic targets including vaccine drug candidates against Coronaviruses in the light of current scientific knowledge. Using an integrative approach to the understanding of Coronaviruses structure, function and immunobiology, the contributors provide a synopsis of novel mechanisms by which Coronaviruses can be treated.  

Key basic and clinical research laboratories from major universities, academic medical hospitals, biotechnology and pharmaceutical laboratories around the world have contributed articles that review present research activity on the role of heat shock proteins in human diseases and importantly project the field into the future. The book is a must read for graduate students. medical students, basic science researchers and postdoctoral scholars in the fields of Cancer Biology, Oncology, Cardiovascular Diseases, Microbiology, Inflammation, Translational Medicine, Clinical Research, Biotechnology, Cell & Molecular Medicine, Pharmaceutical Scientists and Researchers involved in Drug Discovery.