Computer Aided Pharmaceutics and Drug Delivery: An Application Guide for Students and Researchers of Pharmaceutical Sciences

ISBN-13: 9789811651793 / Angielski / Twarda / 2022 / 786 str.

Vikas Anand Saharan

Spis treści

1.​ History and Present Scenario of Computers in Pharmaceutical Research and Development

2. Historical Developments on Computer Applications in Pharmaceutics

3. Computer Aided Formulation Development

4. Quality-by-Design in Pharmaceutical Development

5. Teaching Principles of DoE as an Element of QbD for Pharmacy Students

6. Computer-Assisted Manufacturing of Medicines

7. Computer Aided Biopharmaceutical Characterization: Gastrointestinal Absorption Simulation and In Silico Computational Modeling

8. Computer Simulation and Modeling in Pharmacokinetics and Pharmacodynamics

9. Physiologicallly Based Pharmacokinetic Modelling

10. Computers in Clinical Development

11. Artificial Intelligence (AI)

12. Robotic Automation of Pharmaceutical and Life Science Industries

13. Soft Robots for the Delivery of Drugs

14. Use of Computers and Internet in Scholarly Information Retrieval

15. Patent Searching

16. Computer Aided Drug Design (CADD)

17. Quantitative Structure Property Relationship (QSPR) Modeling Applications in Formulation Development

18. Modeling Approaches for Studies of Drug-Polymer Interactions in Drug Delivery Systems

19. Computers in Pharmaceutical Analysis

20. Telemedicine

21. Bioinformatics in Drug-Design and Delivery

22. Statistical Modeling Techniques

23. Molecular Modelling of Nanoparticles

24. Pharmaceutics Informatics: Bio/chemoinformatics in Drug Delivery

25. Computer-aided Development and Testing of Human Extra-thoracic Airway Models for Inhalation Drug Delivery

O autorze

Vikas Anand Saharan had obtained his B.Pharm from SBSPGI Dehradun, master’s from NIPER Mohali, and PhD from Mohanlal Sukhadia University Udaipur. He has 20 years of teaching and research experience in pharmacy, published 60+ papers in journals, presented 75+ papers in conferences, and supervised 39+ M.Pharm and 2 PhD thesis. He has authored 3 books and 19 book chapters. He has received an award for GATE guidance and appreciation awards for teaching and research. He is a reviewer and editorial board member of various national and international journals. He is a recipient of grant-in-aid under the AICTEMODROBS project. Presently he is also entrusted with the responsibilities of chief program coordinator for PhD and nodal officer for AISHE at Sardar Bhagwan Singh University.

Blurb

This book examines the role of computer-assisted techniques for discovering, designing, optimizing and manufacturing new, effective, and safe pharmaceutical formulations and drug delivery systems. The book discusses computational approaches, statistical modeling and molecular modeling for the development and safe delivery of drugs in humans. The application of concepts of QbD (Quality by Design), DoE (Design of Experiments), artificial intelligence and in silico pharmacokinetic assessment/simulation have been made a lot easier with the help of commercial software and expert systems. This title provides in-depth knowledge of such useful software with illustrations from the latest researches. The book also fills in the gap between pharmaceutics and molecular modeling at micro, meso and maro scale by covering topics such as advancements in computer-aided Drug Design (CADD), drug-polymer interactions in drug delivery systems, molecular modeling of nanoparticles and pharmaceutics/bioinformatics. 

This book provides abundant applications of computers in formulation designing and characterization are provided as examples, case studies and illustrations. Short reviews of software, databases and expert systems have also been added to culminate the interest of readers for novel applications in formulation development and drug delivery. 

Computer-aided pharmaceutics and drug delivery is an authoritative reference source for all the latest scholarly update on emerging developments in computed assisted techniques for drug designing and development. The book is ideally designed for pharmacists, medical practitioners, students and researchers.