Computational Pharmacokinetics

ISBN-13: 9780367388843 / Angielski / Miękka / 2019 / 184 str.

Anders Kallen

Opis

This book outlines the fundamental concepts and models of pharmacokinetics (PK) from a mathematical perspective based on clinically relevant parameters. It covers the analysis of PK data, discusses several physiological aspects to help understand the concepts, and explains processes using real-life data from pharmaceuticals. In addition, the author looks at the relationship between drug concentration and effect, known as PK/pharmacodynamics (PD) modeling. This book will enable readers to thoroughly grasp the computational factors of PK modeling.

Spis treści

Introduction. Empirical Pharmacokinetics. Numerical Methods for PK Parameter Estimation. Physiological Aspects on Pharmacokinetics. Modeling the Distribution Process. PK/PD Modeling. References. Appendices. Index.

O autorze

Kallen, Anders