Section I. General Principles 1 Surgical Anatomy of the Cranial Base: Transcranial and Endonasal Approaches 2 The Pathology of Tumors and Tumorlike Lesions of the Skull Base 3 Imaging of Skull Base Neoplasms 4 Head, Neck, and Neuro-otologic Assessment of Patients with Skull Base Tumors 5 Anesthesia and Intraoperative Monitoring of Patients with Skull Base Tumors 6 Endoscopic Endonasal Skull Base Surgery 7 Reconstruction of Skull Base Defects 8 Radiotherapy for Skull Base Tumors: Principles and Techniques 9 Clinical Applications of Radiotherapy for Skull Base Tumors 10 Management of Benign Skull Base Tumors in Neuro-oncology: Systemic Cytotoxic and Targeted Therapies 11 Rehabilitation of Speech and Swallowing of Patients with Tumors of the Skull Base 12 Neuropsychological Assessment of Patients with Skull Base Tumors 13 Cerebrovascular Management in Skull Base Tumors 14 Quality of Life and Measures of Outcome for Patients with Skull Base Tumors 15 Pediatric Skull Base Surgery Section II. Site-Specific Considerations 16 Surgical Management of Tumors of the Nasal Cavity, Paranasal Sinuses, Orbit, and Anterior Skull Base 17 Nasopharyngeal Carcinoma 18 Clival Tumors 19 Tumors of the Infratemporal Fossa 20 Tumors of the Parapharyngeal Space 21 Tumors of the Temporal Bone 22 The Evaluation and Management of Sellar Tumors 23 Tumors of the Cavernous Sinus and Parasellar Space 24 Tumors of the Petrous Apex 25 Tumors of the Cerebellopontine Angle 26 Tumors of the Jugular Foramen 27 Tumors of the Craniovertebral Junction 28 Tumors of the Orbit Section III. Tumor-Specific Considerations 29 Squamous Cell Carcinoma of the Nasal Cavity and Paranasal Sinuses 30 Nonsquamous Cell Carcinoma of the Nasal Cavity and Paranasal Sinuses 31 Esthesioneuroblastoma 32 Melanoma of the Nasal Cavity and Paranasal Sinuses 33 Sarcomas of the Skull Base 34 Angiofibromas and Other Vascular Tumors of the Skull Base 35 Chordomas and Chondrosarcomas of the Skull Base 36 Meningiomas 37 Schwannomas of the Skull Base 38 Paragangliomas of the Head and Neck 39 Pituitary Adenomas 40 Craniopharyngiomas 41 Epidermoids, Dermoids, and Other Cysts of the Skull Base 42 Fibro-Osseous Lesions of the Skull Base