Complement in Health and Disease

ISBN-13: 9780792388234 / Angielski / Twarda / 1993 / 383 str.

Keith Whaley; K. Whaley; M. Loos

Opis

The complement system plays a major role in the host's defence against infections and in immune complex diseases. Although it is known to consist of a number of serum and membrane proteins that interact through a cascade, there is still a poor understanding of the exact nature of the components and their complex interaction. Many of the biological consequences of complement activation also await elucidation.

Spis treści

Series Editor's Foreword. 1. Introduction; J.M. Weiler. 2. The Phylogeny and Evolution of the Complement System; A.W. Dodds, A.J. Day. 3. Structure and Organisation of Complement Genes; K.B.M. Reid, R.D. Campbell. 4. Synthesis of Complement Components in Liver and at Extra-Hepatic Sites; H.R. Colten, R.C. Strunk. 5. Genetic Deficiencies of the Complement System: An Overview; F.S. Rosen. 6. Human Complement Deficiency States and Infection; P. Densen. 7. Complement, Immune Complexes and Immune Complex Disease; Y.C. Ng, J.A. Schifferli. 8. Hereditary Angio-Oedema; M.K. Frank. 9. Molecular Genetics of C1 Inhibitor and Hereditary Angio-Oedema; M. Tosi. 11. CR3 and its Relationship to Other Phagocytic Receptors; J.B. Weitzeman, S.K.A. Law. 11. Anaphylatoxins; J. Kohl, D. Bitter-Suermann. 12. Cellular Responses to the Membrane Attack Complex; B.P. Morgan. 13. Complement in Diseases of the Nervous System; B.P. Morgan. Index.