Comparative Veterinary Pharmacology, Toxicology and Therapy: Proceedings of the 3rd Congress of the European Association for Veterinary Pharmacology a

ISBN-13: 9789401083430 / Angielski / Miękka / 2011 / 576 str.

A. S. J. P. a. M. Van Miert; M. G. Bogaert; M. Debackere

Opis

The third congress ofthe European Association for Veterinary Pharmacology and Toxicol ogy (EAVPT) was held in Ghent, Belgium, from 25 to 29 August 1985. Part I of the Proceedings of this congress contains the abstracts of all invited lectures, oral communi cations and poster communications, presented at the congress. The invited lectures are now published (this volume) in extenso as Part II of the Proceedings. The editors wish to thank all invited speakers for their active contribution to the success of the third congress of EAVPT. They are very grateful to Dr. P. De Backer for compiling all manuscripts, Dr. P. Lees for scientific amendments, Miss B. Vermeesch and Dr. R. Lefebvre for preparing the camera ready copy and MTP Press for literary advice and publishing. A. S. J. P. A. M. van Miert M. G. Bogaert M. Debackere xi Contributors AMEND J.F. Department of Anatomy and Physiology, Atlantic Veterinary College. University of Prince Edward Island. Charlotte town. P.E.I. CIA 4P3. Canada. ANIKA S.M. Department of Veterinary Physiology and Pharmacology. University of Nigeria, Nsukka. Nigeria. ARGENZIO R.A. Department of Anatomy, Physiological Sciences. and Radio logy, School of Veterinary Medicine. North Carolina State University. Raleigh, NC 27606. USA. ARONSON A.L. Clinical Pharmacology Unit. School of Veterinary Medicine. North Carolina State University, Raleigh. North Carolina 27606. USA. AUCOIN D.P. The Animal Medical Center. 510 E 62nd Street. New York. New York 10021. USA. xiii xiv COMPARATIVE VETERINARY PHARMACOLOGY, TOXICOLOGY AND THERAPY BAARS A.J."

Spis treści

Anaesthesia, Neuroleptanalgesia and Sedation.- 1 Influence of halothane anaesthesia, after xylazine premedication, on serum calcium concentration in the horse.- 2 Pharmacological properties of benzodiazepines in animals.- 3 Effects of halogenated inhalational anaesthetics on respiration in dogs.- 4 Analgesic activity of butorphanol in horses: dosage titration and clinical studies.- Teaching Veterinary Pharmacology.- 5 Postgraduate training in the veterinary pharmacology.- 6 The teaching of veterinary pharmacology and toxicology.- Drug Delivery Systems and Bioavailability.- 7 Design and evaluation of studies on drug delivery systems.- 8 Potential of new drug delivery systems in veterinary medicine.- 9 Influence of injection site on the depot effect of procaine penicillin in dogs.- 10 Influence of food on absorption of antimicrobial drugs.- Smooth Muscle Pharmacology.- 11 Pharmacology of the (fore)-stomach smooth muscles.- 12 Smooth muscle pharmacology of the large intestine.- 13 Recent advances in the pharmacological control of the intestinal and colonic motor profiles.- 14 Cholinergic-like effect of the H2-receptor antagonist ranitidine on the rabbit small intestine.- Comparative Pharmacokinetic Studies.- 15 Comparative pharmacokinetics: introductory remarks.- 16 Comparative neonatal pharmacokinetics.- 17 Comparative pharmacokinetic studies of sulphonamides.- 18 Species differences in protein binding.- Drug Residue Toxicology.- 19 The target animal species in drug toxicity studies: an evaluation of its usefulness and limitations.- 20 The use of pharmacokinetics in chronic toxicity testing.- 21 The Food Animal Residue Avoidance Databank (FARAD): a computer databank of the pharmacokinetics of drugs, pesticides and environmental chemicals in food animals.- Inflammation and Anti-Inflammatory Drugs Immunomodulation.- 22 Modulation of autonomic receptor function by Haemophilus influenzae in the respiratory system.- 23 Impairment of pulmonary homeostatic and antimicrobial defence mechanisms by infectious bovine rhinotracheitis and parainfluenza-3 virus infections.- 24 The potential of biological response modifiers in the treatment of malignancies in animals and man.- 25 Immunological defence mechanisms as a target for antibiotics.- Drug Biotransformation.- 26 Comparative aspects of drug conjugation in laboratory animals, exotic species and man.- 27 Hepatic microsomes as models for comparative metabolism in vivo.- 28 Pharmacokinetics, hydroxylation and acetylation of sulphadimidine in mammals, birds, fish, reptiles and molluscs.- 29 Disposition and metabolism of 14C-mebendazole in sheep and poultry.- Diarrhoea.- 30 Modulation of intestinal ion absorption and secretion by enterotoxins, hormones and neurotransmitters.- 31 Species and age-dependent factors governing the clinical severity of diarrhea.- 32 Antidiarrhoeal therapy.- 33 The effects of veterinary drugs based on humic acids in the treatment of enteritis in young animals.- Clinical Toxicology.- 34 Drug reactions leading to toxicity.- 35 Clinical toxicology of an antibiotic ionophore (monensin) in ponies and horses; diagnostic markers and therapeutic considerations.- 36 Mycotoxins and nnycotoxicoses in Europe.- Pathophysiological Models in Pharmacology, Miscellaneous.- 37 Role of animal disease models in evaluating the efficacy of antimicrobial agents.- 38 Effects of disease states on drug binding to serum proteins.- 39 Tickborne fever: efficacy and effects on pharmacokinetics of some chemotherapeutic agents in the goat.- 40 Statistical methods for evaluation of drug efficacy in animal models.- 41 Pharmacology of carbadox in the pig.- Opiates, Opioids and Neuropeptides.- 42 Opioid peptides and their receptors.- 43 Endorphin systems, pain and addiction.- 44 Opioid effects on gastrointestinal motor and secretory functions.- 45 Central nervous system control of feeding behaviour by some neuropeptides in sheep.- Drug Use and Regulation.- 46 The use in animals of drugs licensed for human use only.- 47 The use in small animal medicine of drugs licensed for human purposes.- 48 The use in animals of drugs licensed for human use: the situation in Sweden.- 49 Regulation of drug usage in veterinary medicine: the situation in Germany.- 50 Do residues of antimicrobial drugs constitute a microbiological risk for the consumer?.