Compact Handbook of Computational Biology

ISBN-13: 9780367393915 / Angielski / Miękka / 2019 / 572 str.

A. K. Konopka; M. James C. Crabbe

Opis

Written by a dynamic team of highly regarded researchers, many of whom pioneered current methodologies in computer-assisted research in the life sciences, this interdisciplinary handbook covers terminology, software, and applications of computational biology. It provides clearly written yet authoritative descriptions of methods and practical examples of their use supported by 975 cited references. Highlights include methods for pragmatic analysis of nucleic acid and protein sequences and structures, definition and detection of motifs in nucleic acid and protein sequences, protein structure prediction, and discrete modeling of biopolymers.

Spis treści

Foreword. Contributors. Introduction: Computational Biology in 14 Brief Paragraphs. Biomolecular Sequence Analysis. Introduction to Pragmatic Analysis of Nucleic Acid Sequences. Motifs in Sequences: Localization and Extraction. Protein Sequence Analysis and Prediction of Secondary Structural Features. Biopolymer Structure Calculation and Prediction. Discrete Models of Biopolymers. Protein Structure Folding and Prediction. DNA-Protein Interactions: Target Prediction. Genome Analysis and Evolution. Methods of Computational Genomics: An Overview. Computational Aspects of Comparative Genomics. Computational Methods for Studying the Evolution of the Mitochondrial Genome. Appendix 1: Computational Biology: Annotated Glossary of Terms. Appendix 2: A Dictionary of Programs for Sequence Analysis. Index.

O autorze

Andrzej K. Konopka, M. James C. Crabbe