Colorectal Cancer: Evidence-Based Chemotherapy Strategies

ISBN-13: 9781588297518 / Angielski / Twarda / 2006 / 292 str.

Leonard B. Saltz

Opis

Management options for patients with colorectal cancer have undergone d- matic changes over the past decade. Whereas at the start of 1996 only one drug, 5-Fluorouracil, was available for the treatment of this disease, a mere 10 yr later, six drugs are licensed for use in colorectal cancer, and others are in the late phases of clinical development. Likewise, surgical and ablative options, as well as an array of supportive medications, have shown substantial progress and undergone a dramatic proliferation over the past decade. With the increased number of therapeutic options from which to choose, the clinician is better able to offer effective therapy to the patient with colorectal cancer. The clinician is challenged, however, to keep up with the rapidly changing landscape and the rapidly emerging data that shape the options for treatment today and tom- row. In this text, leaders in the management of colorectal cancer review the current literature that has led us to where we are today. Critical evaluations of the data are offered, and evidence-based recommendations are made.

Spis treści

Understanding the Biology of Colorectal Cancer William Grady Chemoprevention of Colorectal Cancer Paul Engstrom Screening and Surveillance Arnold Markowitz First Line Cytotoxic Chemotherapy Options Ed Chu Angiogenesis Inhibitors in Colorectal Cancer Charles Blanke EGFR Inhibitors in Colorectal Cancer Paulo Hoff Salvage Chemotherapy Strategies in Metastatic Disease Heinz-Joseph Lenz Adjuvant Chemotherapy of Stage II and III Colon Cancer Richard Goldberg Management of Locally Advanced Rectal Cancer David Cunningham Chemotherapy Issues with Resectable Metastases of Colorectal Cancer Axel Grothey Percutaneous Ablative Therapies for Colorectal Cancer Karen Brown Diagnostic Imaging Modalities in Metastatic Colorectal Cancer Larry Schwartz Nursing Issues in Colorectal Cancer Chemotherapy Ellen Hollywood and Deborah Semple Pain Management in Colorectal Cancer Vivek Tim Malhotra Future Prospects for New Agents and Strategies in Colorectal Cancer Chris Takimoto