Colonic Diseases

ISBN-13: 9780896039612 / Angielski / Twarda / 2003 / 556 str.

John R. McKean; Timothy R. Koch; Timothy R. Koch

Opis

Management of Colonic Diseases provides a bridge between basic and clinical research and the clinical care of individuals with colonic disorders. It is divided in four sub-sections: colo-rectal physiology, mechanisms of disease, clinical investigation of disease processes and management of colo-rectal disorders. It also examines mechanisms of disease involved in the development of colonic disorders and provides an overview of techniques used in clinical research involving patients with disorders of the colon. It should benefit readers by introducing new areas of potential treatment not presently available for patients with often-chronic symptoms.

Recenzje

"...recommended for use by trainee clinician-scientists and by basic scientists who desire a perspective on their work-a bridge between basic and clinical research...an attractive, high-quality production, well illustrated and comprehensively referenced...refreshingly manageable, easy to read, and generally filled with useful information." - New England Journal of Medicine

"The book contains brief, generally well-written chapters surveying a wide range of topics of interest to most gastroenterologists. Dedicated chapters not found in most gastoenterology textbooks include coverage of aging and the gastrointestinal tract and the interpretation of colonic biopsy specimens in patients with diarrhea." - American College of Physicians

"Valuable reading for gastroenterologists interested in bridging the gap between basic and clinical research and disease processes in the continuously changing field of coloni c disorders." - Digestive and Liver Disease

"...this textbook has its greatest value for those interested in the basics of colonic morphology and function...Chapters on anorectal and colonic motility studies are probably among the best I have ever read on these subjects." - Practical Gastroenterology

"The book is well organized and written clearly with many references helpful to the reader seeking additional knowledge on the subject. This book is mostly intended for gastroenterologists, gastrointestinal fellows, all specialist physicians including radiologists and family physicians who daily treat gastrointestinal disorders." - Journal of Clinical Imaging

Spis treści

Part I. Colorectal Physiology Absorption-Secretion and Epithelial Cell Function Pradeep K. Dudeja, Ravinder Gill, and K. Ramaswamy Normal Motility and Smooth Muscle Function Mary Francis Otterson Neural Regulation of Colonic Motor Function Kenton M. Sanders and Terence K. Smith Mucin and Goblet Cell Function Samuel B. Ho and Laurie L. Shekels Endocrine Cells of the Colon Sebastian G. de la Fuente, Christopher R. Mantyh, and Theodore N. Pappas Micronutrients Emmanuel C. Opara Aging Emmanuel C. Opara and Timothy R. Koch Immunology of the Gastrointestinal Tract Jonathan R. Fulton, Cynthia A. Cunningham, and Christopher F. Cuff Colonic Lymphatics Stacey A. Weiland and Yang K. Chen Probiotics and the Colon: Therapeutic and Prophylactic Uses Thomas J. Borody and Patricia L. Conway Physiology and Pathophysiology of Colorectal Sensory Processes Michael D. Crowell and Brian E. Lacy Part II. Investigation of Disease Processes Oxidative Stress Emmanuel C. Opara Genetic Testing for Colon Cancer Russell F. Jacoby and Carolyn E. Cole Inflammation Cynthia A. Cunningham, Jonathan R. Fulton, and Christopher F. Cuff Epidemiologic Studies and Outcomes Research in Colonic Diseases John F. Johanson Colonoscopy Donald G. Seibert Interpretation of Colonic Biopsies in Patients with Diarrhea Sarah M. Dry, Galen R. Cortina, and Klaus J. Lewin Anorectal Manometry Devang N. Prajapati and Walter J. Hogan Endoanal and Endorectal Ultrasound Lisa M. Gangarosa Colonic Transit and Motility William J. Snape, Jr. Defecography and Related Radiologic Techniques Vincent H. S. Low Cross-Sectional Imaging of the Large Bowel Diego R. Martin, Ming Yang, and Paul Hamilton Part III. Colorectal Disease Hirschsprung's Disease and Neonatal Disorders Carol Lynn Berseth Acute Megacolon, Acquired Megacolon, and Volvulus Marc Stauffer and Timothy R. Koch Diverticular Disease Gordon L. Telford, Susan W. Telford, and Mary F. Otterson Current Understanding of Colorectal Neoplasia Melanie B. Thomas and Robert A. Wolff Constipation Anne Lutz-Vorderbruegge and Arnd Schulte-Bockholt Crohn's Disease Amit G. Shah and Stephen B. Hanauer Ulcerative Colitis Bret A. Lashner Irritable Bowel Syndrome Michael Camilleri Ischemic Colitis Peter Grübel and David R. Cave Surgical Treatments for Colonic Diseases Joseph P. Muldoon and Steven J. Stryker Anorectal Disorders Mohammed M. H. Kalan and Bruce A. Orkin Index

Blurb

With an aging population prone to colorectal disorders and with the quickening pace of medical discovery, there is a need for an up-to-date survey of the field. In Colonic Diseases, Timothy R. Koch, MD, has assembled a panel of innovative basic researchers, esteemed clinical investigators, and well-known clinicians to bridge the gap between basic and clinical research and the day-to-day care of patients with colonic disorders. As a foundation for better understanding, the authors review what is currently known about normal colonic physiology, explain the mechanisms of disease involved in the development of colonic disorders, and highlight important clues for potential therapies. Their review of the diagnosis and treatment of common colonic disorders covers colorectal neoplasia, inflammatory bowel disease (IBD), ulcerative colitis, diverticular disease, Crohn's disease, and constipation. Here the authors fully discuss potential symptoms, pathological and radiological findings, the differential diagnosis, and presently recommended modes of evaluation and therapy, including the use of probiotics. New areas of potential treatment not presently available for patients with chronic symptoms are also examined, along with the advanced treatment techniques currently in use at the Cleveland Clinic (for ulcerative colitis), The University of Chicago (for Crohn's disease), the Mayo Clinic (for irritable bowel syndrome), and the MD Anderson Cancer Center (for colorectal cancer).
Timely and cutting-edge, Colonic Diseases explains the origins and treatment of common colorectal disorders, blending the molecular mechanisms of disease with new outcomes and epidemiological research to improve our present and future understanding of colonic diseases and their management.