Part I. Basic Principles of Cognitive Enhancement: 1. Cognition and its impairment in schizophrenia and related psychotic disorders; 2. The brain that builds itself: the phenomenon of neuroplasticity; 3. Cognitive enhancement: historical overview and principles; Part II. Approaches to Cognitive Enhancement: 4. Getting ready for cognitive enhancement: patient engagement, stabilization and integration; 5. Computer-based approaches to cognitive enhancement; 6. Individual and group approaches to cognitive enhancement; 7. Psychopharmacological approaches, cognitive enhancement, and brain stimulation; Part III. Personalizing and Optimizing Cognitive Enhancement: 8. Who responds best? Predictors and moderators of cognitive enhancement; 9. Choosing the right treatment for the right patient; 10. Approaches to assessment and monitoring treatment response; 11. Research in cognitive enhancement: challenges and opportunities.