Clues for Differential Diagnosis of Neuromuscular Disorders

ISBN-13: 9783031339233 / Angielski / Twarda / 2023

Opis

This book evaluates muscle and nerve biopsies. It creates a more analytical view of neuromuscular diseases in the light of clinical findings. Diseases that occur mostly in muscle or nerve tissue may show common clinical findings. Addressing these two issues together will make it easier to understand the diseases. Neuromuscular diseases, normal histology, embryology, and physiopathology of muscles and nerves are discussed with a main focus on differential diagnosis. The book also presents the most cost-effective and easiest-to-follow algorithms for the differential diagnosis of diseases.

Spis treści

Chapter 1. A Quick Glance At The Neuromuscular Disorders.- Chapter 2. Understanding Of Muscle And Nerve Tissue.- Chapter 3. The Procedure Of Nerve Biopsy.- Chapter 4. The Procedure Of Muscle Biopsy.- Chapter 5. Preparation Of Muscle And Nerve Biopsy.- Chapter 6. Normal Muscle And Nerve: How To Read A Muscle Or Nerve Biopsy?.- Chapter 7. Molecular Diagnostic Procedures And Genetics In Neuromuscular Disorders.- Chapter 8. Radiological Procedures Used In Differential Diagnosis Of Neuromuscular Disorders.- Chapter 9. Physical Examination, Electrophysological Procedures And Laboratory Tests Used In Differential Diagnosis Of Neuromuscular Disorders.- Chapter 10. Peripheral Neuropathies.- Chapter 11. Disorders Of The Neuromuscular Junction.- Chapter 12. Muscular Dystrophies.- Chapter 13. Congenital Myopathies.- Chapter 14. Metabolic And Mitochondrial Myopathies.- Chapter 15. Approach To The Differential Diagnosis Of Hypotonia In Infancy.- Chapter 16. Inflammatory Myopathies.- Chapter 17. Toxic And Drug- Induced Myopathies.- Chapter 18. Myopathies Associated With Systemic Disorders And Ageing.- Chapter 19. A Quick Glance At The Therapetic Approaches Of Neuromuscular Disorders.

O autorze

Dr. Gulden Diniz is a pathology professor at Izmir Democracy University, and also a microbiologist and basic oncologist (Ph.D.). She worked as the chief of pathology at Dr. Behçet Uz Children's Hospital and Tepecik Training and Research Hospital. She has experience in paediatric and perinatal pathology, renal pathology, molecular pathology, neuropathology, and hematopathology. She is especially experienced in muscle and nerve biopsies. In the 17 years she has been involved in muscle and nerve biopsies, she has reported 1450 muscle and 150 nerve biopsies. For 17 years, Dr. Diniz decidedly used microscopic pictures in all her reports. In the summer of 2010, she followed the nerve and muscle biopsy examinations as a volunteer observer pathologist with Caroline Sewry, Janice Holton, and Sebastian Brandtner at London UCL Neurology Institute for 2 months. Similarly in 2018, she has followed the transplantation pathology examination as a volunteer observer pathologist with Phillip Ruiz at Miami University. Her recent article about the calpainopathies was published at 14 February 2022 by Springer: Berk Ozyilmaz, Ozgur Kirbiyik, Taha R Ozdemir, et al. Experiences in the molecular genetic and histopathological evaluation of calpainopathies. Neurogenetics 2022.