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Kategorie szczegółowe BISAC

Chronic Hepatitis C Virus: Advances in Treatment, Promise for the Future

ISBN-13: 9781461411918 / Angielski / Twarda / 2011 / 332 str.

Shiffman, Mitchell L.
Chronic Hepatitis C Virus: Advances in Treatment, Promise for the Future Shiffman, Mitchell L. 9781461411918 Springer, Berlin - książkaWidoczna okładka, to zdjęcie poglądowe, a rzeczywista szata graficzna może różnić się od prezentowanej.

Chronic Hepatitis C Virus: Advances in Treatment, Promise for the Future

ISBN-13: 9781461411918 / Angielski / Twarda / 2011 / 332 str.

Shiffman, Mitchell L.
cena 602,40
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Chronic Hepatitis C Virus: Lessons from the Past, Promise for the Future documents the monumental advances that have been made in our understanding of chronic HCV during the past decade. The first section reviews the natural history of chronic HCV, how this virus can affect other organs in addition to the liver, and whether treating chronic HCV alters the natural history of this disease. Section 2 reviews the advances that have been made in the treatment of chronic HCV during the past decade with interferon based therapy. Separate chapters on response guided therapy and how to manage the adverse events associated with these medications provide the physician with the concepts required to more effectively treat chronic HCV now and in the future. As the genetics of virologic response have recently been elucidated, a chapter is devoted to helping the clinician understand how genes that modulate disease processes and their treatment are identified and utilized in clinical care. Section 3 deals with the future of HCV treatment and specific inhibitors of HCV. Specific chapters explain how targets for drugs are identified and how drugs are then developed and tested; how mutations of HCV develop and how anti-viral agents will affect this process; the most up to date data regarding the treatment of chronic HCV with peginterferon, ribavirin and anti-viral agents; and the potential to treat chronic HCV with just oral anti-viral agents and without peginterferon and ribavirin in the future. The final section of this book covers issues related to liver transplantation in patients with chronic HCV. Separate chapters review the natural history of chronic HCV in liver transplant recipients and the impact of utilizing HCV positive donors. The volume concludes with chapters that cover the treatment of chronic HCV both prior to and after liver transplantation with potent anti-viral agents. Chronic Hepatitis C Virus: Lessons from the Past, Promise for the Future is a valuable resource for all physicians caring for patients with chronic HCV.

Chronic Hepatitis C Virus: Advances in Treatment, Promise for the Future documents the monumental advances that have been made in our understanding of chronic HCV during the past decade. The first section reviews the natural history of chronic HCV, how this virus can affect other organs in addition to the liver, and whether treating chronic HCV alters the natural history of this disease. Section 2 reviews the advances that have been made in the treatment of chronic HCV during the past decade with interferon based therapy. Separate chapters on response guided therapy and how to manage the adverse events associated with these medications provide the physician with the concepts required to more effectively treat chronic HCV now and in the future. As the genetics of virologic response have recently been elucidated, a chapter is devoted to helping the clinician understand how genes that modulate disease processes and their treatment are identified and utilized in clinical care. Section 3 deals with the future of HCV treatment and specific inhibitors of HCV. Specific chapters explain how targets for drugs are identified and how drugs are then developed and tested; how mutations of HCV develop and how anti-viral agents will affect this process; the most up to date data regarding the treatment of chronic HCV with peginterferon, ribavirin and anti-viral agents; and the potential to treat chronic HCV with just oral anti-viral agents and without peginterferon and ribavirin in the future. The final section of this book covers issues related to liver transplantation in patients with chronic HCV. Separate chapters review the natural history of chronic HCV in liver transplant recipients and the impact of utilizing HCV positive donors. The volume concludes with chapters that cover the treatment of chronic HCV both prior to and after liver transplantation with potent anti-viral agents. Chronic Hepatitis C Virus: Advances in Treatment, Promise for the Future is a valuable resource for all physicians caring for patients with chronic HCV.

Kategorie:
Nauka, Medycyna
Kategorie BISAC:
Medical > Gastroenterologia
Medical > Internal Medicine
Wydawca:
Springer, Berlin
Język:
Angielski
ISBN-13:
9781461411918
Rok wydania:
2011
Wydanie:
2012
Ilość stron:
332
Waga:
0.85 kg
Wymiary:
25.4 x 17.8
Oprawa:
Twarda
Wolumenów:
01

From the reviews:

"This book is an important contribution to the field. ... This well-written, concise, and current book will find a home on the shelves of many hepatologists and gastroenterologists. In addition, because it is so readable, it should be useful for students, GI/hepatology fellows, and midlevel providers dealing with patients and doing research. ... This is a concise, updated, and well-written book that belongs in the libraries of healthcare providers and researchers in the field of HCV infection as well as medical institutions." (Paul Angulo, Doody's Review Service, November, 2012)

"Chronic Hepatitis C Virus: Advances in Treatment, Promise for the Future represents a timely new text that is focused on the natural history, treatment, and liver transplantation for chronic hepatitis C virus (HCV) infection. ... an excellent background reference for MD and PhD students, trainees, and clinicians in understanding the scientific basis for current management of chronic HCV infection and highlighting key areas for future investigation. ... is a welcome addition to any library and true to its name ... ." (Richard Sterling and Joseph Lim, Gastroenterology, Vol. 143 (6), 2012)

Section I: Natural History of Chronic HCV

 

Ch. 1- Epidemiology of Chronic HCV

            Gary Davis

           

Ch. 2- Acute HCV     

            Katja Deterding

            Heiner Wedemeyer

            Michael P. Manns

 

Ch. 3- Assessing the Progression of Chronic HCV to Cirrhosis

            Xavier Forns

 

Ch. 4- Chronic HCV and Steatosis

            Dawn McDowell Torres

            Stephen A. Harrison

 

Ch. 5- Chronic HCV and Hepatocellular Carcinoma

            Morris Sherman

 

Ch. 6- Extrahepatic Manifestations of Chronic HCV

            Antonio Craxi

            Vincenza Calvaruso

 

Ch. 7- Chronic HCV and HIV Co-infection 

            Patrick Ingiliz

            Maud Lemoine

            Yves Benhamou

 

Ch. 8- Chronic HCV in Patients with Renal Disease

            Paul Martin

            Fabrizio Fabrizi

 

Ch. 9- Does Treatment Alter the Natural History of Chronic HCV

            Bruce Bacon

            Fasiha Kanwal

 

Section II: Treatment of Chronic HCV with Interferon Based Therapy

 

Ch. 10- Treatment with Interferon and Ribavirin

            Stuart Roberts

            William Kemp

 

Ch. 11- Immune Modulators and Other Agents

            Edgar D. Charles

            Ira M. Jacobson

 

Ch. 12- Measuring HCV RNA and Assessing Virologic Response

            Jean-Michel Pawlotsky

           

Ch. 13- Response Guided Therapy

            Mitchell Shiffman

 

Ch. 14- Managing the Side Effects of Therapy

            Curtis Cooper

 

Ch. 15- The Genetics of Virologic Response

            Andrew J Muir

            Alison B. Jazwinski

 

Ch. 16- Maintenance Therapy with Peginterferon

            Nezem Afdahl

            Raza Malik

 

 

Section III: Anti-viral Therapy for Chronic HCV

 

Ch. 17- Anti-viral Targets in HCV

            Bernd Kronenberger

            Stefan Zeuzem

 

Ch. 18- Mutations and the Development of Anti-viral Resistance

            Geoffrey Dusheiko

            Anna Maria Geretti

 

Ch. 19- Peginterferon, Ribavirin and Anti-viral Triple Therapy

            Patrick Marcellin

            Nathalie Boyer

            Tarik Asselah

 

Ch. 20- Treating Chronic HCV without Interferon and/or Ribavirin

            Ed Gane

 

Ch. 21- Maintenance Therapy with Oral Anti-viral Agents

            Donald M. Jensen

            Andrew Aronsohn

 

Section IV: Liver Transplantation for Chronic HCV

 

Ch. 22- Natural History of Chronic HCV after Liver Transplantation         

            Michael Charlton

            Bart J. Veldt

 

Ch. 23- Use of HCV Positive Organs in Patients with and without Chronic HCV

            Robert Brown

            Elizabeth C. Verna

 

Ch. 24- Treating HCV Prior to Liver Transplantation

            Greg Everson

            Alvaro Martinez-Camacho

            Brett E. Fortune

 

Ch. 25- Treating HCV after Liver Transplantation

            Sammy Saab

            Michael Chang

            Hubert Sung

           

 

 

Ch. 2- Acute HCV     

            Katja Deterding

            Heiner Wedemeyer

            Michael P. Manns

 

Ch. 3- Assessing the Progression of Chronic HCV to Cirrhosis

            Xavier Forns

 

Ch. 4- Chronic HCV and Steatosis

            Dawn McDowell Torres

            Stephen A. Harrison

 

Ch. 5- Chronic HCV and Hepatocellular Carcinoma

            Morris Sherman

 

Ch. 6- Extrahepatic Manifestations of Chronic HCV

            Antonio Craxi

            Vincenza Calvaruso

 

Ch. 7- Chronic HCV and HIV Co-infection 

            Patrick Ingiliz

            Maud Lemoine

            Yves Benhamou

 

Ch. 8- Chronic HCV in Patients with Renal Disease

            Paul Martin

            Fabrizio Fabrizi

 

Ch. 9- Does Treatment Alter the Natural History of Chronic HCV

            Bruce Bacon

            Fasiha Kanwal

 

Section II: Treatment of Chronic HCV with Interferon Based Therapy

 

Ch. 10- Treatment with Interferon and Ribavirin

            Stuart Roberts

            William Kemp

 

Ch. 11- Immune Modulators and Other Agents

            Edgar D. Charles

            Ira M. Jacobson

 

Ch. 12- Measuring HCV RNA and Assessing Virologic Response

            Jean-Michel Pawlotsky

           

Ch. 13- Response Guided Therapy

            Mitchell Shiffman

 

Ch. 14- Managing the Side Effects of Therapy

            Curtis Cooper

 

Ch. 15- The Genetics of Virologic Response

            Andrew J Muir

            Alison B. Jazwinski

 

Ch. 16- Maintenance Therapy with Peginterferon

            Nezem Afdahl

            Raza Malik

 

 

Section III: Anti-viral Therapy for Chronic HCV

 

Ch. 17- Anti-viral Targets in HCV

            Bernd Kronenberger

            Stefan Zeuzem

 

Ch. 18- Mutations and the Development of Anti-viral Resistance

            Geoffrey Dusheiko

            Anna Maria Geretti

 

Ch. 19- Peginterferon, Ribavirin and Anti-viral Triple Therapy

            Patrick Marcellin

            Nathalie Boyer

            Tarik Asselah

 

Ch. 20- Treating Chronic HCV without Interferon and/or Ribavirin

            Ed Gane

 

Ch. 21- Maintenance Therapy with Oral Anti-viral Agents

            Donald M. Jensen

            Andrew Aronsohn

 

Section IV: Liver Transplantation for Chronic HCV

 

Ch. 22- Natural History of Chronic HCV after Liver Transplantation         

            Michael Charlton

            Bart J. Veldt

 

Ch. 23- Use of HCV Positive Organs in Patients with and without Chronic HCV

            Robert Brown

            Elizabeth C. Verna

 

Ch. 24- Treating HCV Prior to Liver Transplantation

            Greg Everson

            Alvaro Martinez-Camacho

            Brett E. Fortune

 

Ch. 25- Treating HCV after Liver Transplantation

            Sammy Saab

            Michael Chang

            Hubert Sung

           

 

 

Ch. 2- Acute HCV     

            Katja Deterding

            Heiner Wedemeyer

            Michael P. Manns

 

Ch. 3- Assessing the Progression of Chronic HCV to Cirrhosis

            Xavier Forns

 

Ch. 4- Chronic HCV and Steatosis

            Dawn McDowell Torres

            Stephen A. Harrison

 

Ch. 5- Chronic HCV and Hepatocellular Carcinoma

            Morris Sherman

 

Ch. 6- Extrahepatic Manifestations of Chronic HCV

            Antonio Craxi

            Vincenza Calvaruso

 

Ch. 7- Chronic HCV and HIV Co-infection 

            Patrick Ingiliz

            Maud Lemoine

            Yves Benhamou

 

Ch. 8- Chronic HCV in Patients with Renal Disease

            Paul Martin

            Fabrizio Fabrizi

 

Ch. 9- Does Treatment Alter the Natural History of Chronic HCV

            Bruce Bacon

            Fasiha Kanwal

 

Section II: Treatment of Chronic HCV with Interferon Based Therapy

 

Ch. 10- Treatment with Interferon and Ribavirin

            Stuart Roberts

            William Kemp

 

Ch. 11- Immune Modulators and Other Agents

            Edgar D. Charles

            Ira M. Jacobson

 

Ch. 12- Measuring HCV RNA and Assessing Virologic Response

            Jean-Michel Pawlotsky

           

Ch. 13- Response Guided Therapy

            Mitchell Shiffman

 

Ch. 14- Managing the Side Effects of Therapy

            Curtis Cooper

 

Ch. 15- The Genetics of Virologic Response

            Andrew J Muir

            Alison B. Jazwinski

 

Ch. 16- Maintenance Therapy with Peginterferon

            Nezem Afdahl

            Raza Malik

 

 

Section III: Anti-viral Therapy for Chronic HCV

 

Ch. 17- Anti-viral Targets in HCV

            Bernd Kronenberger

            Stefan Zeuzem

 

Ch. 18- Mutations and the Development of Anti-viral Resistance

            Geoffrey Dusheiko

            Anna Maria Geretti

 

Ch. 19- Peginterferon, Ribavirin and Anti-viral Triple Therapy

            Patrick Marcellin

            Nathalie Boyer

            Tarik Asselah

 

Ch. 20- Treating Chronic HCV without Interferon and/or Ribavirin

            Ed Gane

 

Ch. 21- Maintenance Therapy with Oral Anti-viral Agents

            Donald M. Jensen

            Andrew Aronsohn

 

Section IV: Liver Transplantation for Chronic HCV

 

Ch. 22- Natural History of Chronic HCV after Liver Transplantation         

            Michael Charlton

            Bart J. Veldt

 

Ch. 23- Use of HCV Positive Organs in Patients with and without Chronic HCV

            Robert Brown

            Elizabeth C. Verna

 

Ch. 24- Treating HCV Prior to Liver Transplantation

            Greg Everson

            Alvaro Martinez-Camacho

            Brett E. Fortune

 

Ch. 25- Treating HCV after Liver Transplantation

            Sammy Saab

            Michael Chang

            Hubert Sung

           

 

 

Mitchell L.  Shiffman, MD
Liver Institute of Virginia, Bon Secours Health System, Richmond, VA, USA

Chronic Hepatitis C Virus: Advances in Treatment, Promise for the Future documents the monumental advances that have been made in our understanding of chronic HCV during the past decade. The first section reviews the natural history of chronic HCV, how this virus can affect other organs in addition to the liver, and whether treating chronic HCV alters the natural history of this disease. Section 2 reviews the advances that have been made in the treatment of chronic HCV during the past decade with interferon based therapy. Separate chapters on response guided therapy and how to manage the adverse events associated with these medications provide the physician with the concepts required to more effectively treat chronic HCV now and in the future. As the genetics of virologic response have recently been elucidated, a chapter is devoted to helping the clinician understand how genes that modulate disease processes and their treatment are identified and utilized in clinical care. Section 3 deals with the future of HCV treatment and specific inhibitors of HCV. Specific chapters explain how targets for drugs are identified and how drugs are then developed and tested; how mutations of HCV develop and how anti-viral agents will affect this process; the most up to date data regarding the treatment of chronic HCV with peginterferon, ribavirin and anti-viral agents; and the potential to treat chronic HCV with just oral anti-viral agents and without peginterferon and ribavirin in the future. The final section of this book covers issues related to liver transplantation in patients with chronic HCV. Separate chapters review the natural history of chronic HCV in liver transplant recipients and the impact of utilizing HCV positive donors. The volume concludes with chapters that cover the treatment of chronic HCV both prior to and after liver transplantation with potent anti-viral agents. Chronic Hepatitis C Virus: Advances in Treatment, Promise for the Future is a valuable resource for all physicians caring for patients with chronic HCV.



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