Chromosomes Today

ISBN-13: 9783034895873 / Angielski / Miękka / 2012 / 320 str.

Ettore Olmo; Carlo A. Redi

Opis

Chromosomes Today, Volume 13 includes the plenary lectures presented at the 13th International Chromosome Conference, covering the most recent advances in the studies on chromosomes. The contributions in this volume were presented by some of the world's leaders in cytogenetic and molecular research and outline the present status of knowledge on the composition, structure, function and evolution of chromosomes, including, among others, the advancement of the human genome project. The use of cytogenetic studies has greatly increased in the last few years, resulting in a progressive improvement in the available methods that has consequently allowed a more detailed analysis of the molecular organization of eukaryotic chromosomes and a precise in situ localisation of specific gene sequences. This volume of Chromosomes Today provides up-to-date information regarding the topics at the forefront of chromosome research: genetic regulation, imprinting, DNA duplication, meiotic pairing, and the regulation of the...

Spis treści

Chromosomes yesterday: a century of chromosome studies.- one: Chromosome organisation.- The prometaphase bands of human chromosomes: compositional features and gene distribution.- The functional and structural organization of Drosophilaheterochromatin.- RNA, genes, genomes and chromosomes: repetitive DNA sequences in plants.- Color plates.- Non-B DNA structures spatially and sequence-specifically associated with individual centromeres in the human interphase nucleus.- two: Chromosome function and behaviour.- Chromosomes in mitosis: chance and checkpoint.- Genetic control of B chromosome transmission in maize and rye.- Igf2 imprinting in development and disease.- three: Meiosis.- Seeing meiotic chromosomes without seeing them.- Meiosis in budding yeast and in multicellular eukaryotes — similarities and differences.- Meiotic pairing sites and genes involved in segregation of the X and Y chromosomes of Drosophila melanogaster.- four: Chromosome evolution.- Genome evolution in Triticeae.- Karyotypic evolution in Neotropical freshwater fish.- Repetitive DNA as a tool to study the phylogeny of cold-blooded vertebrates.- Comparative gene mapping permits new insights into karyotype evolution in mammals.- Color plates.- five: Medical and cancer cytogenetics.- Chromosome and gene alterations in human cancers in relation to aging.- Xp contiguous gene syndromes: from clinical observation to disease gene identification.- Genetic and cytogenetic studies in inherited cancer: Li-Fraumeni syndrome.- Color plates.- six: Mapping and new methods.- Comparative chromosome painting.- High resolution FISH reveals the molecular and chromosomal organisation of repetitive sequences of individual tomato chromosomes.- Species relationships, introgression and physical mapping in Lolium perenne x Festuca pratensis hybrids.- Smallness: gain and loss in plant chromosome research.- Conclusion.- The future of chromosomes.- Synonymous words.