Cholera Outbreaks

ISBN-13: 9783662522714 / Angielski / Miękka / 2016 / 263 str.

G. Balakrish Nair; Yoshifumi Takeda

Opis

The most feared attribute of the human pathogen Vibrio cholerae is its ability to cause outbreaks that spread like wildfire, completely overwhelming public health systems and causing widespread suffering and death. This volume starts with a description of the contrasting patterns of outbreaks caused by the classical and El Tor biotypes of V. cholerae. Subsequent chapters examine cholera outbreaks in detail, including possible sources of infection and molecular epidemiology on three different continents, the emergence of new clones through the bactericidal selection process of lytic cholera phages, the circulation and transmission of clones of the pathogen during outbreaks and novel approaches to modeling cholera outbreaks. A further contribution deals with the application of the genomic sciences to trace the spread of cholera epidemics and how this information can be used to control cholera outbreaks. The book closes with an analysis of the potential use of killed oral cholera vaccines to stop the spread of cholera outbreaks.

Spis treści

1             Cholera Outbreaks in the Classical Biotype Era – A.K. Siddique and Richard Cash

2.           Cholera outbreaks in the El Tor Biotype Era and the Impact of the New El Tor Variants –Asish K. Mukhopadhyay, Yoshifumi Takeda and G. Balakrish Nair

3.           Cholera Outbreaks in India – Thandavarayan Ramamurthy and Naresh C. Sharma

4.           Cholera Outbreaks in South East Asia –  Kaushik Bharati and S.K. Bhattacharya

5.           Cholera Outbreaks in Africa – Martin Mengel, Isabelle Delrieu, Leonard Heyerdahl and Bradford D. Gessner

6.           The Cholera Outbreak in Haiti: Where and How Did it Begin? – Daniele Lantagne, G. Balakrish Nair, Claudio  F. Lanata and Alejandro Cravioto

7.           Role of Phages in the Epidemiology of Cholera – Shah M. Faruque

8.           Circulation and Transmission of Clones of Vibrio cholerae During Cholera Outbreaks – O. Colin Stine and J. Glenn Morris Jr.

9.           Modelling Cholera Outbreaks – Dennis L. Chao, Ira M. Longini Jr. and J. Glenn Morris Jr.

10.         Genomic science in Understanding Cholera Outbreaks and Evolution of Vibrio cholerae as a Human Pathogen. William P. Robins and John J. Mekalanos

11.         When, How and Where Can Oral Cholera Vaccines be Used to Interrupt Cholera Outbreaks? – John Clemens and Jan Holmgren.