Chemotherapy for Leukemia: Novel Drugs and Treatment

ISBN-13: 9789811098444 / Angielski / Miękka / 2018 / 361 str.

Takanori Ueda

Spis treści

1 An Overview.- Part I Bcr-Abl Tyrosine Kinase Inhibitors (TKIs).- 2 Imatinib: Basic Results.- 3 Imatinib: Clinical Pharmacology and Therapeutic Results.- 4 Dasatinib, Nilotinib, Bosutinib, Ponatinib, and Other TKIs.- Part II New Antibodies for Leukemia.- 5 Rituximab and Alemtuzumab for Chronic Lymphocytic Leukemia: Basic Results.- 6 Rituximab and Alemtuzumab for Chronic Lymphocytic Leukemia: Clinical Pharmacology and Therapeutic Results.- 7 Inotuzumab Ozogamicin for Acute Lymphoblastic Leukemia: Clinical Pharmacology and Therapeutic Results.- 8 Blinatumomab for Acute Lymphoblastic Leukemia: Clinical Pharmacology and Therapeutic Results.- 9 Mogamulizumab in Adult T-cell Leukemia/Lymphoma.- Part III Signaling inhibitors.- 10. FLT3 inhibitors.- Part IV Differentiating Agents.- 11 Retinoic Acid, All-Trans Retinoic Acid (ATRA) and Tamibarotene.- 12 The Molecular Basis of Arsenic Trioxide Treatment for Acute Promyelocytic Leukemia (APL).- 13 Arsenic Trioxide: Clinical Pharmacology and Therapeutic Results.- Part V New Chemotherapeutic Agents Including Antimetabolite.- 14 Nelarabine.- 15 Forodesine.- 16 Clofarabine: Structure, Mechanism of Action, and Clinical Pharmacology.- 17 Clinical Use of Clofarabine for Adults and Children with Leukemia.- 18 Re-Emerging Antimetabolites with Novel Mechanism of Action with Respect to Epigenetic Regulation: Basic Aspects.- 19 Epigenetic Regulator, Re-Emerging Antimetabolites with Novel Mechanism of Action (Azacitidine and Decitabine): Clinical Pharmacology and Therapeutic Results.- Part VI Therapy Targeting Leukemic Stem Cells.- 20 Therapies Targeting Leukemic Stem Cells.

O autorze

Takanori Ueda

Vice-President, University of Fukui Faculty of Medical Sciences,

3-9-1 Bunkyo, Fukui 910-8507, Japan