Challenges in Delivery of Therapeutic Genomics and Proteomics

ISBN-13: 9780123849649 / Angielski / Twarda / 2010 / 686 str.

Misra Amalendu

Opis

Delivery of therapeutic proteomics and genomics represent an important area of drug delivery research. Genomics and proteomics approaches could be used to direct drug development processes by unearthing pathways involved in disease pathogenesis where intervention may be most successful. This book describes the basics of genomics and proteomics and highlights the various chemical, physical and biological approaches to protein and gene delivery.

• Covers a diverse array of topics from basic sciences to therapeutic applications of proteomics and genomics delivery
• Of interest to researchers in both academia and industry
• Highlights what's currently known and where further research is needed

Spis treści

1. The Cell

2. Gene Delivery - Challenges and Opportunities

3. Physical Methods of Gene Delivery

4. Gene Delivery Using Chemical Methods

5. Gene Delivery Using Viral Vectors

6. Applications of Gene Therapy

7. Antisense Oligonucleotides and Rna Interference

8. Proteomics

9. Protein and Peptide Delivery Through Respiratory Pathway

10. Oral Delivery of Proteins and Peptides: Concepts and Applications

11: PARENTERAL DELIVERY OF PEPTIDES AND PROTEINS

12. Other Routes of Protein and Peptide Delivery: Transdermal, Topical, Uterine and Rectal

O autorze

Prof. Ambikanandan Misra is a Director, Pharmaceutical Research at Shobhaben Pratapbhai Patel School Of Pharmacy & Technology Management, SVKM's Narsee Monjee Institute of Management Studies, NMIMS Deemed to be University, Mumbai, Maharashtra, India. He has worked in pharmaceutical sciences for over 40 years developing novel drug delivery systems, and advises the pharmaceutical, biotechnology, food, and cosmetics industries. He has published 8 books, 46 book chapters, and 181 peer-reviewed publications in reputed journals.