Cell Surface Receptors: A Short Course on Theory and Methods: A Short Course on Theory and Methods

ISBN-13: 9780792338390 / Angielski / Twarda / 1995 / 256 str.

Lee E. Limbird

Opis

Cell Surface Receptors: A Short Course on Theory and Methods, Second Edition is a primer for the study of cell surface receptors. The simplified discussion of methods and their underlying principles removes the usual intimidation caused by the specialized vocabulary or sophisticated mathematics that characterize many of the primary papers in this field. In this way, the basic concepts become emphasized. This volume is a starting point: a textbook as well as a manual to which the investigator can return for a refresher course, when needed.

Spis treści

Preface. 1. Historical Perspective. 2. Methods for Characterization of Receptors Based on Receptor-Mediated Responses in Tissue or Intact Cell Preparations. 3. Identification of Receptors Using Direct Radioligand Binding Techniques. 4. Complex Binding Phenomena. 5. The Preparation and Study of Detergent-Solubilized Receptors. 6. The Topographical Fate of Ligand-Receptor Complexes as Reflected by the Properties of Ligand Binding to Intact Cells. Index.