Cell Movement and Cell Behaviour

ISBN-13: 9780045740352 / Angielski / Miękka / 1986 / 336 str.

J. M. Lackie

Opis

Some years ago a book reviewer, perhaps with Freudian honesty, remarked that the book in question 'filled a much needed gap in the literature'. That phrase has haunted the writing of this gap-filler and this preface may be considered an apologia. For a number of years I have found myself teaching various groups of students about cell locomotion and cell behaviour: sometimes science students specializing in cell or molecular biology, sometimes immunologists or pathologists who only wanted a broad background introduction. Those students who were enthusiastic, or who wished to appear so, asked for a general background text (to explain my lectures perhaps), and that is what I hope this book will provide. With luck, other scientists who have only a peripheral interest in cell movement will also find this a useful overview. The more proximate origin of the book was a special 'option' subject which I taught for two years to our Senior Honours Cell Biology students in Glasgow.

Recenzje

The book is written in a friendly disarming style that should carry along those newcomers to the field...As an introduction to cell and molecular biologists wishing to understand more about the movements of living cells the book has no parallel. - The Times Higher Education Supplement

Spis treści

1 Introduction.- 1.1 Why is movement interesting?.- 1.2 What do we mean by ‘movement’?.- 1.3 What causes movement?.- 1.4 An analogy.- 1.5 Motor design — an abstract exercise.- 1.6 How are movements controlled?.- 1.7 Which motor for the task?.- References.- 2 Motors Based on Actomyosin.- 2.1 Introduction.- 2.2 Components of the motor.- 2.3 The basic motor.- 2.4 Linear contractile systems.- 2.5 Non-linear: planar systems.- 2.6 Non-linear: solid systems.- 2.7 Control of the motor.- 2.8 Summary.- References.- 3 Motors Based on Microtubules.- 3.1 Introduction.- 3.2 Structure of microtubules.- 3.3 Dynein.- 3.4 The basic motor.- 3.5 Cilia and flagella.- 3.6 Movement in the mitotic spindle.- 3.7 Movement associated with cytoplasmic microtubules.- 3.8 Summary.- References.- 4 Motors of Other Sorts.- 4.1 Introduction.- 4.2 Bacterial flagella.- 4.3 Other bacterial motors.- 4.4 The spasmoneme of vorticellids.- 4.5 Assembly-disassembly motors.- 4.6 Hydraulic systems.- 4.7 Miscellaneous motor systems.- 4.8 Summary.- References.- 5 Swimming.- 5.1 General.- 5.2 Swimming.- 5.3 Methods of obtaining forward thrust.- 5.4 Control of the direction of ciliary beat.- 5.5 Summary.- References.- 6 Crawling Movement.- 6.1 Introduction.- 6.2 A simplistic analysis of the problem.- 6.3 Amoeba.- 6.4 Fibroblast locomotion.- 6.5 Fibroblast spreading.- 6.6 Movement of other cell types.- 6.7 Summary.- References.- 7 Moving in a Uniform Environment.- 7.1 Introduction.- 7.2 Random walks and internal bias.- 7.3 Effects of changes in environmental properties.- 7.4 Roughness.- 7.5 Rigidity and deformability.- 7.6 Summary.- References.- 8 Anisotropic Environments.- 8.1 General.- 8.2 Trapping and avoidance.- 8.3 Gradients.- 8.4 Flow.- 8.5 Magnetic and electric fields.- 8.6 Gravity.- 8.7 Shape.- 8.8 Rigidity.- 8.9 Summary.- References.- 9 Chemotaxis.- 9.1 General.- 9.2 The problem - a theoretical analysis.- 9.3 Bacterial Chemotaxis.- 9.4 Chemotaxis in Paramoecium.- 9.5 Chemotaxis in the cellular slime-moulds.- 9.6 Chemotaxis in Myxobacteria.- 9.7 Chemotaxis of leucocytes.- 9.8 Summary.- References.- 10 Cell-Cell Interactions.- 10.1 Introduction.- 10.2 Contact inhibition of locomotion.- 10.3 Consequences of contact inhibition.- 10.4 Escape from normal contact inhibition.- 10.5 Invasiveness as a general phenomenon.- 10.6 Summary.- References.