Carvedilol Liposomal Polymeric Gel

ISBN-13: 9786200102973 / Angielski / Miękka / 2019 / 144 str.

Lim Qian Wen; Jaya Raja Kumar Kalaimani; Ngieng Hsern Wei

Opis

In this book, carvedilol-beta-cyclodextrin loaded liposomal gel was developed for efficient incorporation and persistent release of carvedilol. A 3-factors, 2-level Box-Behnken design was used to optimize the process parameters including Cholesterol (A), Poloxamer 188 (B) and Span 40 (C). Six dependent variables refractive index, globule size, viscosity, CDR at 12 hours, gel strength and spreadability were measured as responses. Mathematical equations and response surface plots were to relate the dependent and independent variables using Design-Expert software (DX11).

O autorze

Qian Wen, Lim
Lim Qian Wen is a student of Bachelor of Pharmacy (HONS) in Asian Institute of Medicine Science and Technology (AIMST) University, Kedah, Malaysia. She performed the formulation and optimization of Carvedilol liposomal polymeric gel. She expressed her sincere gratitude to her parents, lecturers and friends for their guidance throughout the project.