Cardiovascular Regeneration Therapies Using Tissue Engineering Approaches

ISBN-13: 9784431239253 / Angielski / Miękka / 2005 / 238 str.

Hidezo Mori; Hidezo Mori; Hikaru Matsuda

Opis

The fact that the cardiovascular system transports oxygen and nutrients to all parts of the body makes any threat to its well-being a serious hazard to organs, tissues, and cells. This fundamental truth underlines the importance of research into cardiovascular regeneration and, therefore, of this collection outlining the latest developments in the field. With input from many of the leading researchers and practitioners, this book describes techniques for therapeutic angiogenesis and vasculogenesis for the treatment of ischemic diseases and examines the current approaches to angiogenic cytokines, cardiovascular stem cells, and tissue-engineering tools. The latest clinical results using bone marrow-derived mononuclear cell therapy for intractable circulatory disorders are also covered. This body of work will be a valuable resource for professionals in the fields of cardiovascular surgery, regenerative medicine, and tissue engineering.

Spis treści

Vascular Precursor Cells and Their Potentiation: EPC and Their Potentiation by Adenovirus Gene Delivery; Potentiation of Regenerative Therapy by Non-Viral Vector, Gelatin Hydrogel; Regeneration of Myocardium Using Bone Marrow Cells.- Development of Myocardial Sheets and Their Cell Sources: Cell Sheet Technology for Myocardial Tissue Engineering; Myocardial Regeneration Therapy with Tissue Implantation of Autologous Myoblast Sheets for Severe Impaired Heart Failure; Cardiovascular Cell Differentiation from ES Cells.- Hybrid Tissues: Preparation and Recellularization of Tissue-Engineered Bioscaffold or Heart Valve Replacement; Biotube Technology for a Novel Tissue-Engineered Blood Vessels; Clinical Application of Tissue-Engineered Blood Vessels.- New Aspects of Angiogenesis: Vascular Regeneration and Remodeling by Circulating Progenitor Cells; Gene Therapy with Hepatocyte Growth Factor for Angiogenesis in Severe Pulmonary Vascular Disease; Basic Fibroblast Growth Factor and Angiogenesis; Gene Therapy for Angiogenesis under a Ventricular Assist System; The Role of Vascular Endothelial Growth Factor (VEGF) on Therapeutic Angiogenesis Using Bone Marrow Cells.- Clinical Results of Therapeutic Angiogenesis and Vasculogenesis: Clinical Survey of Cell Therapy in Japan; A Novel Micro-Angiography Detecting Angiogenesis, Application for Autologous Bone Marrow Mononuclear Cells Transplantation in the Patients with Critical Limb Ischemia; Angiogenesis Induced by Intramyocardial Implantation of Autologous Bone Marrow Mononuclear Cells for the Treatment of Ischemic Heart Disease; Effect of Bone Marrow Transplantation in Patients with Critical Limb Ischemia; Therapeutic Angiogenesis for a Patient with Arteriosclerosis Obliterans by Autologous Transplantation of Bone Marrow Mononuclear Cells; Autologous Bone Marrow Implantation for Burger’s Disease.