Cardiovascular Diseases: Genetic Susceptibility, Environmental Factors and Their Interaction

ISBN-13: 9780128033128 / Angielski / Miękka / 2016 / 252 str.

Papageorgiou, Nikolaos

Opis

Cardiovascular Diseases: Genetic Susceptibility, Environmental Factors and Their Interaction covers the special heritability characteristics and identifying genetic and environmental contributions to cardiovascular health. This important reference provides an overview of the genetic basis of cardiovascular disease and its risk factors. Included are important topics, ranging from lifestyle choices, risk factors, and exposure, to pollutants and chemicals. Also covered are the influences of Mendelian traits and familial aggregation and the interactions and interrelationships between genetics and environmental factors which, when compared, provide a sound understanding of the interplay between inherited and acquired risk factors. The book provides a much needed reference for this rapidly growing field of study. By combining the latest research within the structured chapters of this reference, a better understanding of genetic and environmental contribution to cardiovascular disease is found, helping to substantiate further investigations in the field and design prevention and treatment strategies.

• Provides an overview of the genetic basis of cardiovascular disease and its risk factors
• Reviews several large population-based studies which indicate that exposure to several environmental factors may increase CVD morbidity and mortality, exploring the plausibility of this association by data from animal studies
• Reflects on future studies to help understanding the role of genes and environmental factors in the development and progression of cardiovascular disease

Spis treści

Chapter 1. Summary

Chapter 2. Atherosclerosis and Coronary Artery Disease: From Basics to Genetics

Chapter 3. The Role of Genetics in Acute Coronary Syndrome

Chapter 4. Global Epidemiology and Incidence of Cardiovascular Disease

Chapter 5. Lifestyle Choices, Risk Factors, and Cardiovascular Disease

Chapter 6. The Contribution of Pollutants and Environmental Chemicals in Cardiovascular Disease

Chapter 7. Genetic Susceptibility to Cardiovascular Diseases: From Mendelian Disorders to Common Variants

Chapter 8. Role of Conventional Risk Factors in Genetic Susceptibility to Cardiovascular Diseases

Chapter 9. Genetic Susceptibility in Biochemical and Physiological Traits

Chapter 10. Interactions-Interrelationships Between Genetics and Environmental Factors in Cardiovascular Disease

O autorze

Dr. Papageorgiou has completed his basic training in Greece and continued his cardiology training in Dusseldorf, Germany and thereafter in London, UK. He has trained at the London Heart Hospital, University College London and currently at the Barts Heart Centre, St. Bartholomew's Hospital London UK. He has a strong interest in endothelial function and the mechanisms of atherosclerosis. He also has a strong interest in the role of genetics in cardiovascular disease and holds a PhD degree which is related to that. Currently, he focuses on arrhythmias and the therapeutic approaches which aim to them. He is a reviewer of several international journals, member of the EACVI35. Dr. Papageorgiou currently has over 120 publications in peer reviewed journals, all PubMed listed, and has done more than 100 presentations in international conferences where he has been an invited speaker.