Part I. History.- Chapter 1. History of Cardiac Pacing.- Chapter 2. History of Defibrillation.- Chapter 3. History of Cardiac Mapping.- Chapter 4. History of Optical Mapping.- Part II. Theory of Electric Stimulation and Defibrillation.- Chapter 5. The Bidomain Theory of Pacing.- Chapter 6. Bidomain Theory of Defibrillation.- Chapter 7. The Generalized Activating Function.- Part III. Electrode Mapping and Defibrillation.- Chapter 8. Extracellular Mapping of Arrhythmia.- Chapter 9. Critical Points and the Upper Limit of Vulnerability for Defibrillation.- Chapter 10. Inverse Potential Methods of Cardiac Mapping.- Chapter 11. Monophasic Action Potential.- Part IV. Optical Mapping of Stimulation and Defibrillation.- Chapter 12. Mechanisms of Isolated Cell Stimulation.- Chapter 13. The Role of Microscopic Tissue Structure in Defibrillation.- Chapter 14. Virtual Electrode Theory of Pacing.- Chapter 15. The Virtual Electrode Hypothesis of Defibrillation.- Chapter 16. Simulataneous Optical and Electrical Recording.- Chapter 17. Advanced 3D Optical Mapping.- Chapter 18. Electromechanical Optical Mapping Methods.- Part V. Methodology.- Chapter 19. The Bidomain Model of Cardiac Tissue: From Microscale to Macroscale.- Chapter 20. Newer Models of Cardiac Tissue.- Chapter 21. The Role of Electroporation.- Chapter 22. RF Versus Cryo Ablation.- Chapter 23. Electroanatomical Mapping.- Part VI. Implications for Implantable Devices.- Chapter 24. Lessons for the Clinical Implant.- Chapter 25. Resonance and Feedback Strategies for Low-Voltage Defibrillation.- Chapter 26. Pacing Control of Local Cardiac Dynamics.- Chapter 27. Advanced Methods for Assessing the Stability and Control of Alternans.- Chapter 28. The Future of Implantable Defibrillator.- Chapter 29. Lessons Learnt from Implantable Cardioverter -Defibrillators Recordings.- Part VII. Novel Arrhythmia Therapies.- Chapter 30. Optogenetic Control of Arrhythmias.- Chapter 31. Subcutaneous Defibrillation.- Chapter 32. Future High-Resolution Mapping.- Chapter 33. Conformal Electronics Therapy for Defibrillation.- Chapter 34. Multistage Defibrillation Therapy.- Chapter 35. Implantable Cardioverter Defibrillator to Cardiac Implantable Electronic Device.- Chapter 36. Leadless Pacing.- Chapter 37. Direct His-bundle Pacing.- Chapter 38. Artificial Intelligence/Machine Learning/Deep Learning.- Chapter 39. Wearable Devices for Ambulatory Cardiac and Respiratory Monitoring.

Igor R. Efimov, Ph.D.

Alisann and Terry Collins Professor of Biomedical Engineering

Director, Cardiovascular Engineering Laboratory

The George Washington University

Washington, DC

USA

Fu Siong Ng, M.D., Ph.D.

Clinical Senior Lecturer in Cardiac Electrophysiology

Consultant Cardiologist & Cardiac Electrophysiologist

National Heart & Lung Institute

Imperial College London

London