Carbon Nanomaterials for Biomedical Applications

ISBN-13: 9783319342948 / Angielski / Miękka / 2016 / 576 str.

Mei Zhang; Rajesh R. Naik; Liming Dai

Spis treści

Part I Synthesis and characterization of carbon nanomaterials.- Fullerenes.- Carbon nanotubes.- Graphene.- Nanodiamond.- Carbon nanomaterials doped with heteroatoms.- Carbon nanomaterials with special architectures.- Part II Functionalization of carbon nanomaterials for bio-applications.- Functionalization of fullerenes.- Functionalization of carbon nanotubes.- Functionalization of grapheme.- Functionalization of nanodiamond.- Supermolecular assembly of carbon nanomaterials.- Part III Cytotoxicity and Genotoxicity of carbon nanomaterials.- Cytotoxicity of graphitic carbon nanomaterials.- Cytotoxicity of non-graphitic carbon nanomaterials.- Genotoxicity of carbon nanomaterials .- Interaction of carbon nanomaterials with innate immune systems.- Strategies of generating low toxic carbon nanomaterials for biomedical applications.- Part IV  Biomedical applications of carbon nanomaterials.- Carbon nanomaterials for sensors.- Carbon nanomaterials for drug delivery.- Carbon nanomaterials for gene delivery.- Carbon nanomaterials in regenerative medicine for tissue engineering and cell therapy.- Carbon nanomaterial for NIR imaging and cell tracking.- Carbon nanomaterial for optical imaging and targeted drug delivery.- Carbon nanomaterials as X-ray emitters for biomedical diagnostics.- Carbon nanomaterial-nanoparticle hybrids in multimodal systems for diagnosis, imaging, and treatment of diseases.- Carbon nanomaterials as biomaterials for artificial teeth, bones, and other body parts.- Part V Outlook.- Carbon nanomaterials for biomimetic/bioinspired systems beyond the conventional biomedical engineering.

O autorze

Mei Zhang is a Research Assistant Professor in the Department of Biomedical Engineering.  She also holds a joint appointment in University Hospitals-Case Comprehensive Cancer Center. Zhang's expertise ranges across the synthesis and characterization of polymers and nanomaterials, nanotechnology, tumor immunology, and immunotherapy in the treatment of cancer. Her primary research interest is to apply polymer materials to the design and development of novel nanoparticle systems for multifunctional applications, including gene drug delivery, biomedical imaging, and bio-energy systems (e.g., bio-fuel cells).

Rajesh Naik is the Research Group Leader in the Soft Matter Materials Branch of the Materials and Manufacturing Directorate at Air Force Research Laboratory. Naik’s expertise is in the area of biomaterials, nanomaterials, and bionanotechnology. His interests is primarily in developing biomimetic materials and devices for aerospace applications.

Liming Dai is the Kent Hale Smith Professor in the Department of Macromolecular Science and Engineering at Case Western Reserve University (CWRU). He is also director of the Center of Advanced Science and Engineering for Carbon (CASE4Carbon). Before joining the CWRU, he was an associate professor of polymer engineering at the University of Akron and the Wright Brothers Institute Endowed Chair Professor of Nanomaterials at the University of Dayton. Dr. Dai’s expertise lies across the synthesis, chemical modification and device fabrication of conjugated polymers and carbon nanomaterials for energy-related and biomedical applications.

Blurb

This book covers a wide range of topics relating to carbon nanomaterials, from synthesis and functionalization to applications in advanced biomedical devices and systems. As they possess unique and attractive chemical, physical, optical, and even magnetic properties for various applications, considerable effort has been made to employ carbon nanomaterials (e.g., fullerenes, carbon nanotubes, graphene, nanodiamond) as new materials for the development of novel biomedical tools, such as diagnostic sensors, imaging agents, and drug/gene delivery systems for both diagnostics and clinical treatment. Tremendous progress has been made and the scattered literature continues to grow rapidly.

With chapters by world-renowned experts providing an overview of the state of the science as well as an understanding of the challenges that lie ahead, Carbon Nanomaterials for Biomedical Applications is essential reading not only for experienced scientists and engineers in biomedical and nanomaterials areas, but also for graduate students and advanced undergraduates in materials science and engineering, chemistry, and biology.