Cancer Risk Assessment: A Quantitative Approach

ISBN-13: 9780367403188 / Angielski / Miękka / 2019 / 416 str.

Samuel C. Morris

Opis

Based on the National Academy of Sciences approach to quantitative risk assessment. Emphasizes how an accurate assessment of cancer risk must draw on a wide range of disciplines, such as biology, chemistry, physics, engineering, and the social sciences. Provides tables of Poisson confidence limit fa

Spis treści

Preface -- I. INTRODUCTION -- 1. Introduction -- 2. The Human Cancer Situation -- 3. Hazard Identification -- II. EXPOSURE AND DOSE ASSESSMENT -- 4. Exposure Assessment: General Issues -- 5. Measurement of Exposure and Dose -- 6. Modeling Exposure -- 7. Pharmacokinetics -- III. DOSE-RESPONSE ASSESSMENT -- 8. Toxicology -- 9. Mouse to Man: Extrapolation from Animals -- 10. Quick Methods: Structure-Activity Relationships and Short-Term Bioassay -- 11. Epidemiology -- 12. Combined Approaches to Dose-Response: Putting It All Together -- IV. RISK CHARACTERIZATION AND IMPLICATIONS -- 13. Characterization of Uncertainty -- 14. Risk Characterization, Communication, and Perception -- 15. Quality Assurance, Validation, and Peer Review -- 16. Implications for Risk Management -- 17. Future Directions for Quantitative Health Risk Analysis -- Index.

O autorze

Morris\, Samuel C.