"This is a welcome update given the advances in our understanding of cancer and its treatment. ... best suited for oncologists, general neurologists, neurology residents, and neuro-oncologists, given the topics. Clinicians who are involved in the care of patients with cancer and the care of patients with neurological complications of cancer and its treatment will find this to be a useful reference. ... There are few books on this topic aimed at general neurologists, and this book addresses that need." (Rashmi B. Halker Singh, Doody's Book Reviews, January, 2018)
Part I: Overview
1: The Prevalence and Impact of Neurological Disease in Cancer
Part II: Diagnostic Studies
2: Imaging Neurologic Manifestations of Oncologic Disease
3: Other Diagnostic Tools for Neurological Disease in Cancer: EEG, EMG, and Lumbar Puncture
Part III: Nervous System Involvement of Systemic Cancers
4: Brain Metastasis as Complication of Systemic Cancers
5: Leptomeningeal Metastasis as Complication of Systemic Cancers
6: Spinal Metastasis as Complication of Systemic Cancers
7: Peripheral Nervous System Metastases as Complications of Systemic Cancers
Part IV: Neurological Complications of Cancer
8: Headache as Complication of Cancer
9: Seizures as Complications in Cancer
10: Cerebrovascular Complications of Cancer
11: Elevated Intracranial Pressure and Hydrocephalus in Brain Tumor Patients
12: Cognitive Dysfunction, Mood Disorders, and Fatigue as Complications of Cancer
13: Paraneoplastic Syndromes of the Nervous System as Complications of Cancer
Part V: Neurological Complications of Cancer Therapy
14: Neurologic Complications of Radiation Therapy
15: Neurological Complications of Chemotherapy
16: Neurological Complications of Targeted Therapies
17: Neurological Complications of Immune-Based Therapies
18: Neurological Complications of Hematopoietic Stem Cell Transplantation
19: Neurologic Complications of Corticosteroids in Cancer Therapy
20: Central Nervous System Infections in Patients Receiving Cancer Therapies
Part VI: Neurological Complications of Specific Malignancies
21: Neurological Complications of Primary Brain Tumors
22: Neurological Complications of Lung Cancer
23: Neurological Complications of Breast Cancer and Its Treatment
24: Neurological Complications of Gastrointestinal Cancer
25: Neurologic Complications of Genitourinary Cancer
26: Neurologic Complications of Female Reproductive Tract Cancers
27: Neurological Complications of Sarcomas
28: Neurological Complications of Head and Neck Cancer
29: Neurological Complications of Malignant Melanoma
30: Neurological Complications of Leukemia
31: Neurologic Complications of Lymphoma
32: Neurologic Complications of Plasma Cell Dyscrasias
33: Neurologic Complications of Pediatric Systemic Cancer
Part VII: Neurological Complications in Long Term Cancer Survivors
34: Neurological Complications of Cancer and Cancer Therapies in Long Term Survivors
David Schiff, MD
Harrison Distinguished Teaching Professor of Neurology, Neurological Surgery, and Medicine
University of Virginia
Charlottesville, VA
USA
Isabel Arrillaga, MD, PhD
Instructor, Harvard Medical School;
Massachusetts General Hospital
Department of Neurology/Neuro-Oncology
Boston, MA
USA
Patrick Y. Wen, MD
Professor of Neurology, Harvard Medical School;
Dana-Farber/Brigham and Women’s Cancer Center, Center for Neuro-Oncology
Boston, MA
USA
This updated edition provides clinicians from various backgrounds and levels of training the information needed to optimally diagnose and manage neurologic complications of the nervous system. Organized into seven sections, this comprehensive volume begins with an overview of diagnostic studies for neurologic complications involving the nervous system. That is followed by sections on metastatic and non-metastatic complications of cancer involving the nervous system, and the interpretation, diagnosis, and management of common neuro-oncologic symptoms. The next section reviews the neurologic complications of cancer therapy, including corticosteroids, radiation therapy, chemotherapy, targeted molecular therapies, immunotherapies, hematopoietic stem cell transplantation, and infections involving the nervous system. The final section focuses on the most important neurologic complications in cancers arising from specific organs. In addition to capturing the latest advancements in the rapidly evolving fields of oncology and cancer neurology, the goal of this resource is to lead clinicians toward prompt diagnosis and intervention in order to improve patient quality of life.
"This textbook is a valuable resource for medical oncologists and radiation oncologists, as well as neurologists and neuro-oncologists dealing with these patients. … Overall, the chapters are well organized, clearly written, fairly balanced, and reasonably up to date. … I would recommend it as a learning tool to physicians in training (medical students, residents, and fellows) and for more experienced physicians as both a review/ update and a way to gain more in-depth knowledge and insight into the neurologic problems of cancer patients." (John C. Flickinger, International Journal of Radiation Oncology Biology Physics, Vol. 73 (2), 2009)
"The general organization of the book is logical and facilitates its practical and everyday use. … Overall this textbook is very comprehensive and encompasses main neuro-oncological challenges. … Schiff, Kesari and Wen have edited a very elegant and highly practical textbook, written by recognized authorities in their respective fields, which will be used by a wide range of medical and surgical specialists who are confronted on a daily basis with neurological manifestations of cancer in their practice." (I. Radovanovic and G. Zadeh, British Journal of Cancer, Vol. 100 (6), 2009)