Chapter 1: The Quest for Cancer Nanotheranostics: From Nanotechnology to Cancer Nanotechnology
Chapter 2: Targeted Nanotheranostics for Personalized Cancer Therapy
Chapter 3: Cancer-Targeted Nanotheranostics: Recent Advances and Future Perspectives
Chapter 4: Multifunctional Nanoparticles for Targeting Cancer Nanotheranostics
Chapter 5: Nanoparticle-Based Biologic Mimetics for Cancer Nanotheranostics
Chapter 6: Emerging Theranostic Metal-Based Nanomaterials to Combat Cancer
Chapter 7: Emerging Protein and Peptide-Based Nanomaterials for Cancer Therapeutic
Chapter 8: Emerging Lipid-Based Nanomaterials for Cancer Theranostics
Chapter 9: Emerging Polymer-Based Nanomaterials for Cancer Therapeutic
Chapter 10: Emerging Porphyrin-Based Nanomaterials for Cancer Nanotheranostic
Chapter 11: Role of Micro and Nanomotors in Therapeutics and Diagnostics
Chapter 12: Bionanomaterials in Radiopharmaceuticals for Cancer Nanotheranostics
Chapter 13: Safety of Nanobiomaterials for Cancer Nanotheranostics
Chapter 14: Limitations of Current Cancer Nanotheranostics
Index
List of Contributors (Most have confirmed):
Prof. Tomas J Webster
Department of Chemical Engineering, Nanomedicine Science and Technology Center, Northeastern University, Boston, MA, USA
Prof. Gholam Ali Mansoori
Departments of Bio and Chemical Engineering, University of Illinois at Chicago, Chicago, IL, 60607-7052, USA
Prof. Ali Khademhosseini
Department of Bioengineering, University of California-Los Angeles, Los Angeles, CA 90095, USA
Dr. Omid Farokhzad
Laboratory of Nanomedicine and Biomaterials, Brigham and Women's Hospital, Harvard Medical School, USA
Prof. Hamid Ghandehari
Departments of Pharmaceutics and Pharmaceutical Chemistry and Bioengineering, Utah University, USA
Prof. Xing-Jie Liang
Chinese Academy of Sciences (CAS) Center for Excellence in Nanoscience and CAS Key Laboratory for Biological Effects of Nanomaterials & Nanosafety, National Center for Nanoscience and Technology, China
Prof. Marianna Foldvari
Faculty of Pharmaceutical Sciences, School of Pharmacy, Waterloo University, Canada
Prof. Afsaneh Lavasanifar
Department of Chemical and Material Engineering, Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alberta, Canada
Prof. Moein Moghimi
Department of Pharmaceutics and Analytical Chemistry, University of Copenhagen, Denmark
Prof. Ali Nokhodchi
Pharmaceutics Research Laboratory, School of Life Sciences, University of Sussex, Falmer, Brighton, BN1 9QJ, UK
Prof. Richard D. Adams
Department of Chemistry and Biochemistry, University of South Carolina: Columbia, SC, US
Dr. Gareth Williams
UCL School of Pharmacy, London, United Kingdom
Prof. Boon K. Teo
Department of Chemistry, College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, China
Prof. Jeong-Woo Choi
Department of Chemical and Biomolecular Engineering, Sogang University, South Korea
Dr. Megan Brafford May
Department of Pharmacy, Baptist Health Lexington, Lexington, KY, United States
Dr. Muhammad Torequl Islam
Faculty of Pharmacy, Ton Duc Thang University, Ho Chi Minh City, Viet Nam
Dr. Tarique Benbow
Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver, BC, Canada
Dr. Ahmed Awaisu
Department of Clinical Pharmacy and Practice, College of Pharmacy, Qatar University, Doha, Qatar
Dr. Joanna Hikaka
School of Pharmacy, University of Auckland, Private Bag 92019, Auckland, New Zealand
Dr. Gonçalves Salum, F.
School of Health Sciences, Oral Medicine Division, Pontifical Catholic University of Rio Grande do Sul-PUCRS, Porto Alegre, Brazil
Dr. Simon Zakelj
Faculty of Pharmacy, University of Ljubljana, Aškerčeva cesta 7, Ljubljana, Slovenia
Dr. Nirmal Marasini
School of Biomedical Sciences, Faculty of medicine, The University of Queensland, St Lucia, Australia
Dr. Bobby Presley
Department of Health Services Research (HSR), Faculty of Health, Medicine and Life Sciences (FHML), Maastricht University, Maastricht, Netherlands
Dr. Hamed Barabadi
Department of Pharmaceutical Biotechnology, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Dr. Saravanan Muthupandian
Department of Medical Microbiology and Immunology, Division of Biomedical Sciences, School of Medicine, College of Health Science, Mekelle University, Mekelle, Ethiopa
Prof. Toru Maekawa
Graduate School of Interdisciplinary New Science, Toyo University, Kawagoe, Saitama, 350-8585, Japan
Prof. D. Sakthi Kumar
Bio-Nano Electronics Research Centre, Toyo University, Kawagoe, Saitama, 350-8585, Japan
Prof. Sabu Thomas
International & Inter-University Centre for Nanoscience and Nanotechnology, Mahatma Gandhi University, Kottayam
Prof. Suresh Neethirajan
Bionanotechnology Laboratory, School of Engineering, University of Guelph, Guelph, Ontario, Canada N1G 2W1
Dr. V. Gopinath
Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
Dr. Pushpamalar Janarthanan
Department of Polymer & Organic Chemistry,
School of Science,Monash University Malaysia
Prof. Paulraj Rajamani
School of Environmental Sciences, Jawaharlal Nehru University, New Delhi-110 067, India
Dr.Ramovatar Meena
School of Environmental Sciences, Jawaharlal Nehru University, New Delhi-110 067, India
Dr. Selvaraj Arokiyaraj
Department of Food Science and Biotechnology, Sejong University, Seoul, Republic of Korea
Dr. Krishnan Anand
Department of Chemical Pathology, School of Pathology, Faculty of Health Sciences and National Health Laboratory Service, University of the Free State, Bloemfontein, South Africa- 9301
Prof. Hasan Mukhtar
Department of Dermatology, University of Wisconsin, Medical Sciences, Center B-25, 1300 University Avenue, Madison, WI-53706 USA
Prof. Anil A. Chuturgoon
Discipline of Medical Biochemistry, School of Laboratory Medicine and Medical Science, University of KwaZulu-Natal, South Africa
Dr. P. Prakash
Department of Chemistry,Thiagarajar College, Madurai-9Tamilnadu, India
Dr. P. Boomi
Dept. of Bioinformatics, Alagappa University, Karaikudi. Tamil Nadu, India
Dr. Kuthati Yaswanth
Department of Anesthesiology, Cathay General Hospital, Taipei, Taiwan
Dr. Yasodha Krishna Janapati
Associate Professor, School of Pharmacy & Health Sciences, USIU – AFRICA
Prof. Anima Nanda
Biomedical Engineering, Sathyabama University, India
Dr Muthupandian Saravanan
Muthupandian Saravanan Graduated in Microbiology from Madurai Kamaraj University, India and Doctorate with Specialization in Medical Microbiology and Nanomedicine from Sathyabama University, India. Thereafter, He did a Post-Doctoral Research fellowship focusing his research on Nano-biomaterials & their Biomedical Applications (2011-2012). Prior to postdoc, he worked as an Assistant Professor (SG), SRM University, and Department of Biotechnology for six Years, from 2005 -2011. Presently, Dr. Saravanan working as a Professor, Department of Pharmacology Saveetha Dental college, SIMATS, Chennai, India and worked as Associate Professor, Department of Medical Microbiology and Immunology, Division of Bio-medical Sciences, School of Medicine, College of Health Science, Mekelle University, Ethiopia (2012-2021). His Research Specialization: Development of Novel biomaterials Emerging and Re-emerging Infectious disease and Cancer. He has published more than 150 research paper in Peer-reviewed Journal including high impact Journal with more than 8000 citations and h-index of 42 and i10 index of 85 and also three edited books. He has participated more than 75 National and International conferences, Reviewers of more than 100 international peer-reviewed journals and Guest editor/ Editors for various reputed PubMed and Scopus indexed journals. He has received many fellowships and awards notably, IET- Nanobiotechnology premium Awards two times continuously in the year 2019 and 2020, DST-SERC Young Scientist fellowship in 2011, International Fellowship “Advanced Course on Diagnostics” Sponsored by LSH&TM & Fondation Mérieux, in France 2013, International Fellowship “Pertussis: biology, epidemiology and prevention” meeting Sponsored by Fondation Mérieux & WHO in France 2014, International Union of Microbiological Societies (IUMS) travel grant in 2015 to Canada, International Fellowship "Advanced Course on Antibiotics” (AdCAb) Sponsored by Institute of Pasteur and Fondation Mérieux France, 2016. His area of research includes Medical Microbiology, Antimicrobial Resistance, Nanomedicine, Nanomaterials to combat AMR and Cancer.
Dr Hamed Barabadi
Hamed Barabadi (PharmD, PhD) works as an Assistant Professor at the Department of Pharmaceutical Biotechnology, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran. He obtained his PhD at Shahid Beheshti University of Medical Sciences, Tehran, Iran, in 2019. He graduated as a Doctor of Pharmacy (PharmD) from Mazandaran University of Medical Sciences, Sari, Iran, in 2014. Prior to starting his PhD, he served as a pharmaceutical expert at the Food and Drug Administration at the Department of Inspection and Supervision in Golestan Province, Iran, for two years. He owns to his credit a number of research papers and book chapters in high quality peer-reviewed journals. He has received many awards such as IET- Nanobiotechnology premium Awards two times continuously in the year 2019 and 2020. He is Guest editor/Editor for various reputed indexed journals such as Current Nanomedicine, Nanoscience and Nanotechnology-Asia, Frontiers in Pharmacology, Biocell, etc. His research interests lie in the area of pharmaceutical nanobiotechnology, ranging from green synthesis, characterization and optimization of nanobiomaterials to their pharmaceutical potential evaluations such as anticancer, antimicrobial, antioxidant, etc. Moreover, he has collaborated actively with researchers in several other disciplines of pharmaceutical sciences, particularly the nanoformulation of drugs for drug delivery systems and nanomedicine.
Nanotechnology is an interdisciplinary research field that integrates chemistry, engineering, biology, and medicine. Nanomaterials offer tremendous opportunity as well as challenges for researchers. Of course, cancer is one of the world's most common health problems, responsible for many deaths. Exploring efficient anticancer drugs could revolutionize treatment options and help manage cancer mortality. Nanomedicine plays a significant role in developing alternative and more effective treatment strategies for cancer theranostics. This book mainly focuses on the emerging trends using nanomaterials and nanocomposites as alternative anticancer material’s. The book is divided into three main topic areas: how to overcome existing traditional approaches to combat cancer, applying multiple mechanisms to target the cancer cells, and how nanomaterials can be used as effective carriers. The contents highlight recent advances in interdisciplinary research on processing, morphology, structure, and properties of nanostructured materials and their applications to combat cancer.
Cancer Nanotheranostics is comprehensive in that it discusses all aspects of cancer nanotechnology. Because of the vast amount of information, it was decided to split this material into two volumes. In the first volume of Cancer Nanotheranostics, we discuss the role of different nanomaterials for cancer therapy, including lipid-based nanomaterials, protein and peptide-based nanomaterials, polymer-based nanomaterials, metal-organic nanomaterials, porphyrin-based nanomaterials, metal-based nanomaterials, silica-based nanomaterials, exosome-based nanomaterials and nano-antibodies.
In the second volume, we discuss the nano-based diagnosis of cancer, nano-oncology for clinical applications, nano-immunotherapy, nano-based photothermal cancer therapy, nano-erythrosomes for cancer drug delivery, regulatory perspectives of nanomaterials, limitations of cancer nanotheranostics, the safety of nano-biomaterials for cancer nanotheranostics, multifunctional nanomaterials for targeting cancer nanotheranostics, and the role of artificial intelligence in cancer nanotheranostics.