Cancer: How Worthwhile Is Non-Curative Treatment?

ISBN-13: 9783540760832 / Angielski / Miękka / 1998 / 310 str.

Maurice L. Slevin; M. L. Slevin; R. Rubens

Opis

The majority of patients present with extensive cancer and, as a result, most of these have to be treated with 'non-curative' intent. This major and difficult problem has not been previously tackled and this book asks questions such as how does non-curative intent relate to good quality and quantity of life and how effective is this treatment at relieving symptoms? The result is a review of non-curative surgery, radiotherapy and chemotherapy which are all discussed as they relate to the different types and locations of tumours. This book is aimed not just at specialist oncologists but at all those who are involved in the treatment of cancer. Postgraduate students and those new to the area of oncology will find the book a worthwhile review of treatment undertaken with purely palliative intent.

Spis treści

Section 1. Non-Curative Surgery.- 1. Non-Curative Surgery for Upper Gastrointestinal Malignancy.- Oesophageal Carcinoma.- Gastric Cancer.- Liver.- Cholangiocellular Carcinoma.- Pancreatic Cancer.- Conclusion.- References.- 2. Non-Curative Surgery for Cancer of the Large Bowel.- Common Clinical Situations in Palliative Colorectal Cancer.- Surgical Options.- Local Procedures.- Palliative Colorectal Surgery in the Elderly.- Anal Cancer.- Conclusions.- References.- 3. Non-Curative Surgery for Gynaecological Malignancy.- Breast Cancer.- Gynaecological Pelvic Malignancy.- Miscellaneous.- Conclusions.- References.- 4. Non-Curative Urological Surgery for Cancer.- Ureteric Obstruction.- Fistula.- Urological Tumours.- Conclusions.- References.- 5. Non-Curative Neurosurgery for Malignant Brain Tumours.- Historical Background.- Independent Factors.- Operative Treatment.- Tumour Biopsy.- Open Procedures.- Gliomas in Specific Sites.- Technical Advances.- Results of Surgery.- Role of Surgical Intervention Following Recurrence.- Rehabilitation.- Conclusions.- References.- 6. Non-Curative Surgery for Thoracic Malignancies.- Lung.- Pleura.- Chest Wall.- Mediastinum.- Conclusions.- References.- Section 2. Non-Curative Radiotherapy.- 7. Non-Curative Radiotherapy for Lung Cancer.- Non-Small Cell Lung Cancer.- Specific Problems.- Retreatment.- Small Cell Lung Cancer.- Endobronchial Techniques.- Conclusions.- References.- 8. Non-Curative Radiotherapy for Bone Metastases.- Introduction: Prognosis and Clinical Course.- Pathophsiology.- Symptoms.- Radiotherapy in the Treatment of Bone Metastases.- Local External Beam Radiation.- Pathological Fracture.- Spinal Cord Compression.- Extended Field Radiotherapy.- Radioisotopes.- Conclusions.- References.- 9. Part 1 — Non-Curative Radiotherapy for Upper Gastrointestinal Tract Cancer.- Oesophageal Cancer.- Stomach Cancer.- Pancreatic Cancer.- References.- 9. Part 2 — Non-Curative Radiotherapy for Lower Gastrointestinal Tract Cancer.- Rectal Cancer.- Anal Cancer.- References.- 10. Non-Curative Radiotherapy Treatment for Gynaecological Cancer.- Local Problems Amenable to Palliation with Radiotherapy.- Distant Problems.- Doses and Techniques.- Sites for Radiotherapy.- Measuring Outcome.- References.- 11. Non-Curative Radiotherapy for Neurological Cancer.- Problems Encountered in Brain Tumour Patients.- Measurement of Treatment Efficacy.- Conventional Radiotherapy of High-Grade Glioma.- Recurrent High-Grade Glioma.- Low-Grade Gliomas.- Brain Metastases.- Spinal Cord Compression.- Conclusions.- References.- 12. Non-Curative Treatment for Head and Neck Cancer.- Radiotherapy.- Chemotherapy.- Chemo/Radiotherapy.- Unusual Tumour Types.- Conclusions.- References.- Section 3. Non-Curative Chemotherapy.- 13. Non-Curative Chemotherapy for Breast Cancer.- Health Economics.- Hormone Therapy.- Chemotherapy.- Special Sites.- Conclusions.- References.- 14. Non-Curative Chemotherapy for Small Cell Lung Cancer.- Quality of Life in Patients with SCLC.- Staging.- Single Agent Chemotherapy.- Combination Chemotherapy.- Treatment Duration.- Planned vs. “As Required” Chemotherapy.- Non-Cross-Resistant Regimen.- Dose Intensity.- Chemotherapy for Brain Metastases.- Conclusions.- References.- 15. Non-Curative Chemotherapy for Non-Small Cell Lung Carcinoma.- Surgery and Radiotherapy in NSCLC.- Chemotherapy.- Does Chemotherapy Prolong Life in NSCLC?.- Effects of Chemotherapy on Symptoms and Quality of Life.- Conclusions.- Acknowledgements.- References.- 16. Non-Curative Chemotherapy for Gastric Cancer.- Systemic Therapies.- Locally Directed Therapies.- References.- 17. Non-Curative Chemotherapy for Colorectal Cancer.- Systemic Therapies.- Locally Directed Therapies.- Conclusions.- References.- 18. Non-Curative Chemotherapy for Gynaecological Cancer.- Epithelial Ovarian Cancer.- Cervical Cancer.- Endometrial Cancer.- Vulvar Cancer.- References.- 19. Non-Curative Chemotherapy for Patients with Unknown Primary Cancers.- Poorly Differentiated Neoplasm.- Adenocarcinoma of Unknown Primary Site.- Squamous Carcinoma of Unknown Primary Site.- Poorly Differentiated Carcinoma of Unknown Primary Site.- Conclusions.- References.