Burkitt's Lymphoma

ISBN-13: 9781461443124 / Angielski / Twarda / 2012 / 332 str.

Erle S. Robertson

Opis

The study of Burkitt's lymphoma is now in its 6 decade beginning with its discovery by Dr. Dennis Burkitt in equatorial Africa in the mid to late 1950's. A large body of information is available which provides a current understanding of the underlying molecular changes that are linked to the initiation and development of Burkitt's lymphoma. This proposed volume will provide a comprehensive view of Burkitt's Lymphoma from the diagnosis to potential animal models for this disease and include a view from physicians who have a up close view of the patients in populations where the disease is rampant. We expect that this will be an excellent resource for Medical students and faculty as well as educated laypersons who have a person interest in the disease.

Spis treści

Preface.- Introduction.- Diagnosis of Burkitt’s Lymphoma.- Burkitt’s Lymphoma : A View from the Bedside.- Clinical Implications of Burkitt’s Lymphoma.- Definition of Burkitt’s Lymphoma.- Classical and Endemic Burkitt’s Lymphoma.- Sporadic Burkitt’s Lymphoma.- AIDS-Associated Burkitt’s Lymphoma.- Diffuse Large B-Cell Lymphoma and High Grade Diffuse Large B-Cell Lymphoma.- EBV Associated Burkitt’s Lymphoma.- Molecular Biology of Burkitt’s Lymphoma.- Burkitt’s Lymphoma and the Immune Response.- Burkitt’s Lymphoma and the Malaria Connection.- Therapeutic Approaches to Burkitt’s Lymphoma.- Animal Model of Burkitt’s Lymphoma.- Burkitt’s Lymphoma: Future Perspectives.- Index

Blurb

This volume aims to bring together efforts with a patient-oriented focus from physicians to diagnostics and clinical implications of the disease as mostly seen in the equatorial African setting. However, the chapters cover the breadth of studies on Burkitt’s lymphoma with some clues for the potential future of Burkitt’s lymphoma research that can have therapeutic benefits for patients.   

This text explore a range of topics associated with Burkitt’s lymphoma, including molecular biology, diagnosis, its association with AIDS and Malaria, immune responses, therapeutic approaches and a unique view from the bedside. This volume is comprehensive and unique and represents the most up-to-date clinical and research activities on Burkitt’s lymphoma.