Boron Neutron Capture Therapy: Toward Clinical Trials of Glioma Treatment

ISBN-13: 9780306443503 / Angielski / Twarda / 1993 / 279 str.

Detlef Gabel; Ray Moss

Opis

Two dozen substantial papers from a workshop in Petten, the Netherlands, September 1991, present a snapshot of the use of boron neutron capture therapy for the treatment of cancer, at the moment when the results of the first clinical trials on humans were just available, and several countries were c

Spis treści

Opening Speech; E.D. Hondros. Welcome Address; H.H. van der Kroonenberg. Safety and Efficacy in Boron Neutron Capture Therapy; D. Gabel. Some Aspects of BNCT at the Brookhaven National Laboratory; D.D. Joel, et al. INEL BNCT Program Directions with Respect to Clinical Trials of BNCT; R.V. Dorn III. The Department of Energy Research Program in Boron Neutron Capture Therapy; R.W. Wood, D.W. Cole Jr. Current Overview on the Approach of Clinical Trials at Petten; R.L. Moss. Review of the Physics Calculations Performed for the BNCT Facility at the HFR Petten; P. Watkins, et al. From Filter Installation to Beam Characterization; F. Stecher-Rasmussen, et al. Neutron Spectrometry Measurements of the Petten HFR, HB11 Neutron Beam; C.A. Perks, H.J. Delafield. A Semi-Empirical Method of Treatment Planning for Boron Neutron Capture Therapy; C.P.J. Raaijmakers, et al. Present Status of the Three-Dimensional Treatment Planning Methodologies for the Petten BNCT Facility; P. Watkins. A Phase 1 Biodistribution study of p-Boronophenylalanine; J.A. Coderre. RBE in Normal Tissue Studies; R.A. Gahbauer, et al. Treatment planning and optimization for Pion Therapy; H. Blattmann. Dose Calculations Based on Images Reconstructions; F.J. Wheeler, D.E. Wessol. Borocaptate Sodium (BSH) Pharmacokinetics in Glioma Patients; H. Fankhauser, et al. BSH in Patiens with Malignant Glioma: Distribution in Tissue, Comparison between BSH Concentration and Histology; D. Haritz, et al. Macroscopic and Microscopic Biodistribution of BSH in a Rat Glioma Model; C.P. Ceberg, et al. Healthy Tissue Tolerance Studies for BNCT at the High Flux Reactor in Petten-First Results; A. Siefert. Cellular Pharmacokinetics of BNCT Compounds and their Cellular Localization with EELS/ESI; R. Verrijk, et al. Large Animal Model Studies of Normal Tissue Tolerance using an Epithermal Neutron Beam and Borocaptate Sodium; P.R. Gavin, et al. Proposal for Patient Selection Criteria and Follow-up for BNCT in Patients with Supratentorial Malignant Gliomas; H. Fankhauser, G. Stragliotto. A Proposal for Phase 1 Clinical Trials of Glioma Patients; H. Bartelink. Approaches to the Design and Evaluation of Compound for BNCT; A.H. Soloway, et al. The implementation Strategy for BNCT Trials in Australia; B.J. Allen. Author Index. Participants. Subject Index. [End of file]