Foreword by Professor John Barrett viiForeword by Professor John Goldman viiiList of Contributors ixSection 1 Late effects concepts 11 Introduction to long-term survivorship after hematopoietic cell transplantation 3Bipin N. Savani and André Tichelli2 International Blood and Marrow Registries: trends on long-term data collection 6Rachel Phelan, Jakob R. Passweg, Helen Baldomero, Minako Iida, Yoshiko Atsuta, Shinichiro Okamoto, Mahmoud Aljurf, Feras Alfraih, and Bronwen E. Shaw3 Long-term follow-up program and transplant clinic setup 14André Tichelli, Bipin N. Savani, Shahrukh K. Hashmi, Navneet S. Majhail, and Alicia Rovó4 Telemedicine in patient care of long-term transplant survivors 25Catherine J. Lee, Mihkaila Wickline, and Mary E.D. Flowers5 Long-term follow-up calendar 33André Tichelli, Bipin N. Savani, Shahrukh K. Hashmi, Navneet S. Majhail, and Alicia Rovó6 Late effects post-allogeneic hematopoietic stem cell transplantation 38Shahrukh K. Hashmi and Yoshihiro Inamoto7 Late effects post-autologous hematopoietic stem cell transplantation 47Rajshekhar Chakraborty and Betty K. Hamilton8 Long-term follow-up of children 58Paul A. Carpenter9 Graft-versus-host disease and late effects after hematopoietic stem cell transplantation 73David Michonneau, Aurélien Sutra del Galy, and Gérard Socié10 Screening and prevention guidelines for hematopoietic cell transplant survivors 80Neel S. Bhatt, J. Douglas Rizzo, and Navneet S. Majhail11 Biology of survivorship after blood or marrow transplantation 92Smita BhatiaSection 2 Specific late effects 10112 Second malignancies 103Aurélien Sutra del Galy, David Michonneau, and Gérard Socié13 Anti-infective prophylaxis, immunization and prevention of late infectious complications 112Per Ljungman14 Seasonal respiratory viral infections 119Nosha Farhadfar, Zeina Al-Mansour, and John R. Wingard15 Monitoring and management of hepatitis B, C, and HIV infection before and after transplantation 132Enric Carreras and Montserrat Rovira16 Skin chronic GVHD 140Attilio Olivieri, Anna Campanati, Gaia Goteri, and Andrea Bacigalupo17 Ocular complications 166Alicia Rovó, André Tichelli, and Yoshihiro Inamoto18 Management of oral and dental complications 176Hildegard T. Greinix19 Thyroid disease: monitoring and management guidelines 183Juliana Matthews, Leslee Matheny, and Shubhuda Jagasia20 Pretransplant considerations in gender, reproductive, and sexual health 189Dana Shanis, Jeanne Murphy, Kate Debiec, Betty K. Hamilton, Shawna Boyle, and Pamela Stratton21 Posttransplant Considerations in Gender, Reproductive, and Sexual Health 198Jeanne Murphy, Dana Shanis, Kate Debiec, Betty K. Hamilton, Shawna Boyle, and Pamela Stratton22 Fertility issues, fertility preservation, and pregnancy outcome in long-term survivors 211Alicia Rovó, Alison W. Loren, André Tichelli, and Nina Salooja23 Sexual Dysfunction in Long-Term Survivors 221Rebecca L. Hunter, Sarah Thilges, Janna Gordon, Kristy Luke, Karla Cavazos, Emilee Moeke, Colleen Bruen, and Sunita Nathan24 Late non-infectious pulmonary complications 231Ayman O. Soubani25 Cardiac and arterial complications 241Alicia Rovó and André Tichelli26 Cardiovascular risk factors 251Kimberley Doucette and Minoo Battiwalla27 Gastrointestinal complications 260Sumona Bhattacharya, Steven Pavletic, and Theo Heller28 Hepatic Complications 271Christy Ann L. Gilman, Christopher Koh, Steven Pavletic, and Theo Heller29 Renal complications 278Insara Jaffer Sathick and Sangeeta Hingorani30 Posttransplantation bone disease: prevalence, surveillance, prevention, and management 287Christine N. Duncan31 Late neurologic complications 300Enrico Maffini32 Neurocognitive dysfunction 312David Buchbinder and Angela Scherwath33 Psychological Distress 330Anna Barata, Aasha I. Hoogland, and Heather S. L. Jim34 Evaluation and management of fatigue in survivors of allogeneic hematopoietic stem cell transplantation 337Sandra A. Mitchell35 Social Issues 349Sanghee Hong and Navneet S. Majhail36 Health-related quality of life in adult and pediatric survivors 355Sandra A. Mitchell, Lori Wiener, Jenny Hoag, Abigail Fry, and Margaret F. BevansSection 3 Supportive care and patients reported outcomes 38137 Immunosuppressive agents and monitoring in long-term survivors 383Kathryn A. Culos and Katie S. Gatwood38 Nutritional support and nutritional supplementation 393Shigeo Fuji39 Daily routines and healthy lifestyle guidelines 397Melissa Logue40 Prevalent psychosocial adjustment issues and solutions: lifestyle and social challenges 402Katrina M. Stokes41 Complementary and alternative medicine in HSCT 406Ibrahim N. Muhsen, Bipin N. Savani,, and Shahrukh K. Hashmi42 Impact of adherence in outcome of long-term survivors 413Corien Eeltink and Annika Kisch43 Prominent role of allied health professionals 418Catherine E. Lucid44 Patient reported outcomes 420Hélène Schoemans45 Caregivers of long-term survivors 428Angela Moreschi Woods46 Patient's perspective: memoir of a recovered lymphomaniac 434Michael BrownAppendix 1 Commonly used transplant-related medications in long-term survivors 442Kathryn A. Culos and Katie S. GatwoodAppendix 2 The eGVHD App 445Hélène SchoemansIndex 448
About the EditorsBipin N. Savani is Professor of Medicine and Director of Long-Term Transplant and Survivorship Clinic at Vanderbilt University Medical Center and Veterans Affairs Medical Center, Nashville, TN, USA.André Tichelli is Professor Emeritus of Hematology, Division of Hematology, University Hospital Basel, Switzerland.