Blood Substitutes: New Challenges

ISBN-13: 9781461286592 / Angielski / Miękka / 2011 / 210 str.

Robert M. Winslow; Kim D. Vandegriff; Marcos Intaglietta

Opis

This book is not a "proceedings" volume. Rather the chapters are essays by experts in the field of blood substitutes, invited by the editors to con tribute to the 1996 "Current Issues in Blood Substitutes Research and Development" course given in San Diego, March 18-21. The contributors were selected because of their expertise in areas deemed by the editors to be critical to the advancement of the field. The course, as in past years, is heavily influenced by feedback from par ticipants, and by research in this and related fields. In addition to the didactic lectures (for which these chapters are the foundation), the course also offers the opportunity for presentation of research reports, progress reports from the various companies currently commercializing products, and round table discussions of selected subjects. Thus, we are grateful to past participants for their helpful comments. Production of a book, especially on a short timeline, is not an easy feat."

Spis treści

1 Blood Substitutes: 1995 in the Literature.- 2 Blood Substitutes: What is the Target?.- 3 Blood Flow Distribution During Shock.- 4 Blood Substitute Oxygen Carriers Designed for Clinical Applications.- 5 Interaction of Hemoglobin with Nitric Oxide and Carbon Monoxide: Physiological Implications.- 6 Biological Consequences of Cross-linked Hemoglobin in Animal Models of Surgery and Endotoxemia.- 7 Hemorrhagic Disorders After Administration of Glutaraldehyde-polymerized Hemoglobin.- 8 Microvascular Oxygen Distribution: Effects Due to Free Hemoglobin in Plasma.- 9 Experimental Simulation of Oxygen Transport in Microvessels.- 10 Carbon Dioxide Transport by Hemoglobin-Based Blood Substitutes.- 11 Non-phospholipid Liposomes: A Novel Method for the Preparation of Hemoglobin Containing Lipid Vesicles.- 12 Hemoglobin-Endotoxin Interactions.