Bisphosphonates and Tumor Osteolysis

ISBN-13: 9783642836701 / Angielski / Miękka / 2011 / 78 str.

Kurt W. Brunner; Herbert Fleisch; Hans-J Rg Senn

Opis

This volume informs the reader about basic chemical and experimental aspects of the bisphosphonates, their application in neoplastic hypercalcemia, and the basic effects of these drugs in neoplastic osteolysis. Initial reports, which need confirmation by larger randomized studies, also deal with the long-term application and possibly favorable influence of bisphosphonates in metastatic bone disease. It is vital for medical oncologists and interested internists to keep abreast of recent information in this new area of clinical cancer research.

Spis treści

Bisphosphonates: A New Class of Drugs in Diseases of Bone and Calcium Metabolism.- Pathophysiological Aspects and Therapeutic Approaches of Tumoral Osteolysis and Hypercalcemia.- Use of Clodronate and Calcitonin in Hypercalcemia Due to Malignancy.- Treatment of Tumor Hypercalcemia with Clodronate.- Treatment of Tumor-Induced Osteolysis by APD.- Clodronate Therapy of Metastatic Bone Disease in Patients with Prostatic Carcinoma.- Effect of Long-Term Bisphosphonate Treatment on Morbidity Due To Bone Metastases in Breast Cancer Patients.