Biotherapeutic Agents and Infectious Diseases

ISBN-13: 9781475746525 / Angielski / Miękka / 2013 / 316 str.

Gary W. Elmer; Lynne McFarland; Christina Surawicz

Opis

Authoritative investigators active in the discovery, development, and application of biological anti-infective agents concisely review their use and potential in preventing and treating human disease. Focusing on biotherapeutic entities that have been tested in controlled studies, the prominent experts illuminate the scientific underpinnings of their therapeutic power, assess their possible risks in the treatment of infectious diseases, and outline the research needed to better define their effectiveness. In addition, they also consider how biotherapeutic agents may be genetically engineered for maximum intestinal and vaginal production of bioactive substances in vivo. Biotherapeutic Agents and Infectious Diseases brings together all the evidence needed to understand and capitalize on the considerable promise of this significant new class of biotherapeutic entities.

Recenzje

"This book does a good job explaining what a biotherapeutic agent is and what role it may play in the areas of microbiology, infectious disease resistance, and treatment options. . .It is written in a manner that those in a wide variety of disciplines would have no difficulty understanding. . .[the book is] interesting and challenging to some of our goals in the area of chemotherapy-resistant pathogens of the future."-Doody's Health Sciences Book Review Journal

Spis treści

Quality Control and Regulatory Issues for Biotherapeutic Agents, L. V. McFarland. Mechanisms of Action of Biotherapeutic Agents, J.-P. Butts. Pharmacokinetics of BTA, S. W. Martin, A. C. Heatherington, and G. W. Elmer. Influences on the Normal Microbial Flora, K. Orrhage and C. Nord. Immunological Effects of Biotherapeutic Agents, P. Marteau and C. Cellier. Biotherapeutic Agents in the Prevention of Antibiotic-Associated Diarrhea, C. M. Surawicz. Biotherapeutic Agents for Clostridium difficile-Associated Disease, L. V. McFarland. Biotherapeutic Agents in the Management of Pediatric Diarrheal Disease, J. M. Saavedra. Biotherapeutic Agents and Adult Diarrhea, S. Salminen, E. Isolauri, and E. Salminen. Biotherapeutic Agents as Therapy for Vaginitis, J. D. Sobel. Biotherapeutic Agents to Prevent Cystitis in Women, G. Reid, V. Smeianov, and A. W. Bruce. Risks of Biotherapeutic Agents, C. M. Surawicz and L. V. McFarland. Future Directions for Research on Biotherapeutic Agents: Contribution of Genetic Approaches on Lactic Acid Bacteria, G. Corthier and P. Renault. Index

Blurb

In Biotherapeutic Agents and Infectious Diseases, leading investigators active in the discovery, development, and application of this novel class of anti-infective agents concisely review the use of these special microorganisms in treating human disease. Focusing on biotherapeutic entities that have been tested in controlled studies, the prominent experts illuminate the scientific underpinnings of their therapeutic potential, assess their possible risks in the treatment of infectious diseases, and outline the research needed to better define their effectiveness. In addition, they also consider biotherapeutic agents may be genetically engineered for maximum intestinal and vaginal production of bioactive substances in vivo.
Biotherapeutic Agents and Infectious Diseases brings together all the evidence needed to understand and capitalize on the considerable promise of this significant new class of biotherapeutic entities. As an alternative to antibiotics that increasingly lead to drug-resistant pathogens, the living microorganisms described in this timely and authoritative book will significantly aid today's clinicians in the prevention and treatment of infectious diseases.