Biotargets of Cancer in Current Clinical Practice

ISBN-13: 9781493959464 / Angielski / Miękka / 2016 / 564 str.

Mauro Bologna

Opis

Here is a concise listing of major cancer types, with epidemiology, diagnostic biomarkers, descriptions of genes for prognosis and therapy through biotarget-specific molecular treatments. Covers current debate on patentability of genetic information and more.

Recenzje

From the reviews:

"In this book on clinically significant biotargets in cancer research, every organ system is thoroughly represented with adequate overviews and precise details of the biotargets. ... the book is intended specifically for clinicians in the field, including medical students, residents, pathologists, and oncologists. ... This is a well-written book that attempts to provide a wide spectrum of current scientific information about the clinical management of oncologic patients based on molecular aspects. ... this book achieves its objectives while remaining easy to read." (Natalie Webster, Doody's Review Service, October, 2012)

Spis treści

Ch. 1- Central Nervous System Tumors
 Paolo Aloisi
 Francesco Martella
 Davide Cerone
 Giampiero Porzio
 
Ch. 2- Head and Neck Tumors
 Keith D. Hunter
 Robert Bolt

Ch. 3- Thyroid Cancer
 Laura D. Locati
 Angela Greco
 Maria Grazia Borrello
 Maria Luisa Carcangiu
 Paolo Bossi
 Roberta Granata
 Lisa Licitra

Ch. 4- Targeted Therapies for Non-Small Cell Lung Cancer
 Giulio Metro
 Lucio Crinò

Ch. 5- Non-Hodgkin Lymphomas
 Roberta Zappasodi
 Massimo Di Nicola

Ch. 6- Leukemias
 Lia Ginaldi 
 Massimo De Martinis

Ch. 7- Breast Cancer
 Nadia Rucci
 Luca Ventura
 Anna Teti

Ch. 8- Esophago-Gastric Cancer
 Alex M. Reece-Smith
 Simon L. Parsons 
 Sue A. Watson

Ch. 9- Colorectal Cancer
 David Church
 Rachel Midgley
 David Kerr

Ch. 10- Hepatocellular Carcinoma
 Yasunori Minami
 Masatoshi Kudo

Ch. 11- Biomarkers for Prognosis and Molecularly Targeted Therapy in Renal Cell Carcinoma
 Laura S. Schmidt

Ch. 12- Bladder Cancer
 Andrea Tubaro
 Daniele Santini
 Cosimo De Nunzio
 Alice Zoccoli
 Michele Iuliano

Ch. 13- Biomarkers in Prostate cancer
 Mauro Bologna
 Carlo Vicentini

Ch. 14- Ovarian Cancer
 Jessica Wangui Oribabor
 Allison Ambrosio
 Cesar M. Castro
 Michael J. Birrer

Ch. 15- Uterine Cancer: The Influence of Genetics and Environment on Cell Cycling Pathways in Cancer
 Annekathryn Goodman
 Leslie S. Bradford
 Leslie A. Garrett

Ch. 16- Biotargets in Sarcomas: The Past, Present and a Look into the Future
 Vivek Subbiah
 Razelle Kurzrock

Ch. 17- Melanoma and other skin cancers
 Kim H.T. Paraiso
 Jobin K. John
 Keiran S.M. Smalley

Ch. 18- Molecular pathology of cancer metastasis: suggestions for future therapy
 Adriano Angelucci
 Edoardo Alesse

Ch. 19- Current and future developments in cancer therapy research: miRNAs as new promising targets or tools
 Marilena V. Iorio
 Patrizia Casalini
 Claudia Piovan
 Luca Braccioli
 Elda Tagliabue

O autorze

Mauro Bologna, MD
University of L’Aquila, L’Aquila, Italy

Blurb

Biotargets of Cancer in Current Clinical Practice presents an updated and reasoned review of the current status of knowledge concerning the major cancer types with a special focus on the current biomarkers, genes involved and the potential future targets of innovative therapies. The volume includes for each major cancer type, a comprehensive although concise discussion of epidemiology, affirmed and innovative biomarkers for diagnosis, and descriptions of the relevant genes for prognosis and (individualized) therapy through biotarget-specific new molecular treatments, with the latest information on the validation status of each novel biomarker. Individual chapters are dedicated to the major cancer types, plus a special chapter on metastasis. The present debate on patentability of genetic information applied to diagnostics and therapeutics of cancer is also discussed.