Bioreactors: Animal Cell Culture Control for Bioprocess Engineering

ISBN-13: 9781138749689 / Angielski / Miękka / 2017 / 136 str.

Goutam Saha; Alok Barua; Satyabroto Sinha

Opis

This book presents the design, fabrication, and control of a new type of bioreactor meant especially for animal cell line culture. The new bioreactor, called the "see-saw bioreactor," is ideal for the growth of cells with a sensitive membrane. The authors describe the principle of operation of the see-saw bioreactor and how to automatically control the bioprocess. They also discuss the thorough experimental research they conducted on this prototype bioreactor and define the future scope of work in terms of design, control, and software sensors.

Spis treści

Introduction. Novel see-saw bioreactor. Simulation of bioprocess and development of BIPROSIM: A general purpose simulation program. Dynamic optimization of a bioprocess using genetic algorithm. Bioprocesses and time delay control. Experimentation on the bioreactor. General conclusion and future scope of research.

O autorze

Alok Barua received his bachelor of technology in instrumentation and electronics engineering, master of electronics and telecommunication engineering, and PhD in electrical engineering from Jadavpur University and Indian Institute of Technology (IIT) Kharagpur in 1977, 1980, and 1992, respectively. He is a full professor in the Department of Electrical Engineering, IIT Kharagpur. With more than 30 years of teaching experience at IIT, he has published many papers in his teaching and research areas, including instrumentation, bioreactor design and control, testing and fault diagnosis of analog and mixed-signal circuits, and image processing. He has supervised several MS theses and two PhD theses on bioreactor control and instrumentation. He also holds a patent for the design of the see-saw bioreactor and is a senior member of IEEE.

Goutam Saha earned his BE in electrical engineering, his ME in electronics and telecommunication engineering, and his PhD in electrical engineering from Bengal Engineering and Science University (formerly known as B.E. College) and IIT Kharagpur in 1984, 1989, and 1999, respectively. He worked as a postdoctoral research fellow at Ben Gurion University, Israel, from January to August 2002. He is currently a full professor in the Department of Information Technology, North-Eastern Hill University, Shillong, India. He has more than 25 years of teaching experience in various engineering colleges including the National Institute of Technology (Durgapur), the National Institute of Technical Teachers Training and Research (Kolkata), and other government engineering colleges of West Bengal.

Satyabroto Sinha (deceased) earned a PhD in electrical engineering from the Indian Institute of Technology (IIT) Kharagpur. He taught electrical engineering at IIT Kharagpur from December 1963 to May 2005 (professor, 1982–2002; professor emeritus, 2002–2005). He advised 13 doctoral students, coauthored several books, and published approximately 60 conference and journal papers, nationally and internationally. His area of specialization was instrumentation and control. He was a national coordinator for the Technology Development Mission on Communication, Networking and Intelligent Automation for the Government of India from 1995 to 2000 and was a senior member of the Institute of Electrical and Electronics Engineers and a chartered engineer and fellow of the Institution of Engineers (India).