Biophysics of Infection

ISBN-13: 9783319812182 / Angielski / Miękka / 2018 / 362 str.

Mark C. Leake

Spis treści

The Biophysics of Infection.- Single-molecule observation of DNA replication repair pathways in E. coli.- Investigating the swimming of microbial pathogens using digital holography.- What is the ‘minimum inhibitory concentration’ (MIC) of pexiganan acting on Escherichia coli? – A cautionary case study.- Evolution of drug resistance in bacteria.- Using Biophysics to Monitor the Essential Proton motive Force in Bacteria.- The Type I restriction enzymes as barriers to horizontal gene transfer: determination of the DNA target sequences recognised by Livestock-Associated Methicillin Resistant Staphylococcus aureus Clonal Complexes 133/ST771 and 398.- Biomechanical analysis of infectious biofilms.- Designing a single-molecule biophysics tool for characterizing DNA damage for techniques that kill infectious pathogens through DNA damage effects .- Bacterial Surfaces: Front Lines in Host-Pathogen Interaction.- Biophysical approaches to bacterial gene regulation by riboswitches.- Bugs on a slippery plane: Understanding the motility of microbial pathogens with mathematical modelling.- Transcription regulation and membrane stress management in enterobacterial pathogens.- How biophysics may help us understand the flagellar motor of bacteria which cause infections..- Mechanics of bacterial cells and initial surface colonisation.- Neutron reflectivity as a tool for physics-based studies of model bacterial membranes.- Mechanisms of Salmonella Typhi host-restriction.- Insights into biological complexity from simple foundations.- Force spectroscopy in studying infection.- Imaging Immunity in Lymph Nodes: Past, Present and Future.- Bacterial pathogen biofilms: studying and manipulating evolution.