ISBN-13: 9781439804742 / Angielski / Twarda / 2009 / 224 str.
ISBN-13: 9781439804742 / Angielski / Twarda / 2009 / 224 str.
Designed as a basic reference for researchers in a wide variety of disciplines, this book discusses plant transformation techniques, the generation of transgenic plants, and the engineering of plant viruses to produce vaccine proteins or peptides. It addresses the basis of mucosal immunity using plant-based oral vaccines, organelle targeting for vaccine production, and the role of glycosylation in plant-made mammalian proteins. It also considers vaccine production in entire crops or in large batch cell suspension cultures as well as the development of clinical trials. The book concludes with a risk analysis and discussion of future applications.