Biomedical Photonics Handbook: Therapeutics and Advanced Biophotonics

ISBN-13: 9781420085167 / Angielski / Twarda / 2014 / 767 str.

Tuan Vo-Dinh

Opis

Shaped by Quantum Theory, Technology, and the Genomics Revolution

The integration of photonics, electronics, biomaterials, and nanotechnology holds great promise for the future of medicine. This topic has recently experienced an explosive growth due to the noninvasive or minimally invasive nature and the cost-effectiveness of photonic modalities in medical diagnostics and therapy. The second edition of the Biomedical Photonics Handbook presents recent fundamental developments as well as important applications of biomedical photonics of interest to scientists, engineers, manufacturers, teachers, students, and clinical providers. The third volume, Therapeutics and Advanced Biophotonics, focuses on therapeutic modalities, advanced biophotonic technologies, and future trends.

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Represents the Collective Work of over 150 Scientists, Engineers, and Clinicians"

Designed to display the most recent advances in instrumentation and methods, as well as clinical applications in important areas of biomedical photonics to a broad audience, this three-volume handbook provides an inclusive forum that serves as an authoritative reference source for a broad audience involved in the research, teaching, learning, and practice of medical technologies.

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What s New in This Edition: "

A wide variety of photonic biochemical sensing technologies has already been developed for clinical monitoring of early disease states and physiological parameters, such as blood pressure, blood chemistry, pH, temperature, and the presence of pathological organisms or biochemical species of clinical importance. Advanced photonic detection technologies integrating the latest knowledge of genomics, proteomics, and metabolomics allow sensing of early disease states, thus revolutionizing the medicine of the future. Nanobiotechnology has opened new possibilities for detection of biomarkers of disease, imaging single molecules and "in situ "diagnostics at the single-cell level. In addition to these state-of-the-art advancements, the second edition contains new topics and chapters including:

Fiber Optic Probe Design

Laser and Optical Radiation Safety

Photothermal Detection

Multidimensional Fluorescence Imaging

Surface Plasmon Resonance Imaging

Molecular Contrast Optical Coherence Tomography

Multiscale Photoacoustics

Polarized Light for Medical Diagnostics

Quantitative Diffuse Reflectance Imaging

Interferometric Light Scattering

Nonlinear Interferometric Vibrational Imaging

Nanoscintillator-Based Therapy

SERS Molecular Sentinel Nanoprobes

Plasmonic Coupling Interference Nanoprobes

Comprised of three books: Volume I: Fundamentals, Devices, and Techniques; Volume II: Biomedical Diagnostics; and Volume III: Therapeutics and Advanced Biophotonics, this second edition contains eight sections, and provides introductory material in each chapter. It also includes an overview of the topic, an extensive collection of spectroscopic data, and a list of references for further reading."

Spis treści

Therapeutic and Interventional Techniques. Mechanistic Principles of Photodynamic Therapy. Synthesis and Biological Significance of Porphyrin-based Photosensitizers in Photodynamic Therapy. Lasers in Dermatology. Lasers in Interventional Pulmonology. Lasers in Diagnostics and Treatment of Brain Diseases. Lasers in Ophthalmology. Lasers in Otolaryngology. Therapeutic Applications of Lasers in Gastroenterology. Low-Power Laser Therapy. Image Guided Surgery. Optical Methods for Caries Detection, Diagnosis and Therapeutic Intervention. Nonlinear Interferometric Vibrational Imaging and Spectroscopy. Multifunctional Theranostic Platform: Plasmonic-Active Gold Nanostars. Activity of psoralen-functionalized nanoscintillators against cancer cells upon X-ray excitation. Advanced Biophotonics and Nanophotonics . Living Cell Analysis Using Optical Methods. Amplification Techniques for Optical Detection. Fluorescent Probes in Biomedical Applications. Optical Trapping Techniques in Bioanalysis, . Luminescent Nanoparticle-Based Probes for Bioassays, . Fluorescent Molecular Beacon Nucleic Acid Probes for Biomolecular Recognition. Luminescent Quantum Dots for Diagnositc and Bioimaging Applications. PEBBLE nanosensors for in vitro bioanalysis. Nanosensors for Single-Cell Analyses. SERS Molecular Sentinel Nanoprobes to Detect Biomarkers for Medical Diagnostics. Plasmonic Coupling Interference (PCI) Nanoprobes for Gene Diagnostics. DNA Sequencing using Fluorescence Detection. In Vivo Bioluminescence Imaging as a Tool for Drug Development.

O autorze

Tuan Vo-Dinh is the R. Eugene and Susie E. Goodson Distinguished Professor of biomedical engineering, professor of chemistry, and director of the Fitzpatrick Institute for Photonics at Duke University. He received a B.S. in physics in 1970 from EPFL (Ecole Polytechnique Federal de Lausanne) in Lausanne and a Ph.D. in physical chemistry in 1975 from ETH (Swiss Federal Institute of Technology) in Zurich, Switzerland. Dr. Vo-Dinh has authored over 350 publications in peer-reviewed scientific journals. He is the author of a textbook on spectroscopy and editor of 6 books. He has received numerous awards and holds over 37 U.S. and international patents.