Biomedical Informatics

ISBN-13: 9781934115633 / Angielski / Twarda / 2009 / 270 str.

Vadim Astakhov

Opis

In past decades, the area of bioinformatics has proved to be both dynamic and vital, producing a wide spectrum of novel approaches and assuming an increasingly important role in modern bio-technological development. In Biomedical Informatics, expert researchers explore cutting-edge new advances in the field, providing an overview of novel cyberinfrastructures which are currently under development in various bio-medical centers across the world. Chapters demonstrate various architectures for large-scale collaboration, offer modern approaches currently used in various areas of bioinformatics, and highlight the software challenges associated with large-scale biomedical informatics. Composed in the highly successful Methods in Molecular Biology series format, chapters include a brief introduction, detailed methods, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls. Wide-ranging and innovative, Biomedical Informatics is an essential manual for newcomers to this area, as well as an invaluable addition to the laboratories and offices of the most practiced researchers.

Recenzje

From the reviews: "Technicians and researchers from San Diego, California survey novel cyber-infrastructures that are currently under development in various biomedical centers around the world. They describe several architectures for large-scale collaboration across multiple centers, modern approaches in various areas of bioinformatics, and software challenges and strategies for overcoming them. ... The material could be helpful to practitioners working in bioinformatics or students preparing for it." (SciTech Book News, March, 2010) "This volume in the Methods in Molecular Biology series provides an overview of novel cyberinfrastructures that are fundamental to present-day biomedical informatics. ... Scientists involved in biomedical informatics ... who are active in the field of biomedical research are the intended audience. This includes both first-time and seasoned students and biomedical researchers who are interested in using informatics technologies in their laboratories. ... This is an excellent contribution to the literature dedicated to the study of bioinformatics in biomedical sciences." (Ruben Mestril, Doody's Review Service, February, 2010)

Spis treści

Table of Contents Table of Contents Preface Contributors 1. Management of Information in Distributed Biomedical Collaboratories David B. Keator 2. Enabling Public Data Sharing: Encouraging Scientific Discovery and Education Christine Fennema-Notestine 3. Mediator Infrastructure for Information Integration And Semantic Data Integration Environment for Biomedical Research Jeffrey S. Grethe, Edward Ross, David Little, Brian Sanders, Amarnath Gupta, Vadim Astakhov 4. System Biology of Gene Regulation Michael Baitaluk 5. Current computational methods for prioritizing candidate regulatory polymorphisms Stephen Montgomery 6. Methods of information geometry in computational system biology (Consistency between Chemical and Biological Evolution) Vadim Astakhov 7. Protein Structure Prediction based on Sequence Similarity Lukasz Jaroszewski 8. Applications of Bioinformatics to Protein Structures - How Protein Structure and Bioinformatics Overlap Gye Won Han, Chris Rife, Michael R. Sawaya 9. Knowledge Discovery via Machine Learning for Neuro-degenerative Disease Researchers I. Burak Özyurt, Gregory G. Brown 10. Brain Model of Text Animation as a Data Mining Strategy Tamara Astakhova, Vadim Astakhov 11. Processes Parallelization Using 'Grid Wizard Enterprise' Marco Ruiz 12. Single Sign-On in a Grid Portal Ramil V. Manansala